SynopsisGandotinib is identified as being highly selective for JAK2-V617F and has advanced into human clinical trials for the treatment of several myeloproliferative disorders. The global Gandotinib market was valued at US$ million in 2023 and is anticipated to .....
Synopsis2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone (CAS 32384-65-9) is a synthetic building block which has been used to prepare C-glucosides via the nucleophilic addition of a suitably functionalised aryllithium reagent, followed by a triethylsilane reduction.....
SynopsisPacritinib is an orally bioavailable inhibitor of Janus kinase 2 (JAK2) and the JAK2 mutant JAK2V617F with potential antineoplastic activity. The global Pacritinib market was valued at US$ million in 2023 and is anticipated to reach US$ million by 2030, .....
SynopsisUpadacitinib is a selective JAK inhibitor under the development of AbbVie.ABT-494 is nearly 74 fold selective for Jak1 over Jak2 in cellular assays dependent on specific, relevant cytokines. The global Upadacitinib market was valued at US$ million in 202.....
SynopsisMomelotinib, an aminopyrimidine derivative discovered by high-throughput enzyme and cell-based screening along with the optimization using structure-guided medicinal chemistry, is a potent and selective inhibitor of janus kinase 1 (JAK1), janus kinase 2 (JAK2).....
SynopsisOzanimod is a selective, orally available modulator of the sphingosine-1-phosphate (S1P) receptors S1P1 and SIP5. The global Ozanimod market was valued at US$ million in 2023 and is anticipated to reach US$ million by 2030, witnessing a CAGR of % during .....
SynopsisAmbroxol hydrochloride is a small molecule expectorant and mucolytic agent with antioxidant and antiinflammatory effects. The global Ambroxol Hydrochloride market was valued at US$ million in 2023 and is anticipated to reach US$ million by 2030, witnessi.....
SynopsisSelinexor is a potent and selective inhibitor of chromosome region maintenance 1 protein/exportin 1 (CRM1/XPO1). Selinexor was studied to show in vivo anti-leukaemic efficacy against T-ALL and acute myeloid leukaemia (AML) cells. The global Selinexor mar.....
SynopsisBromhexine hydrochloride is a hydrochloride resulting from the reaction of equimolar amounts of bromhexine and hydrogen chloride. It is used as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised .....
SynopsisTetrahydrofuran bromide is a compound used to synthesize inhibitors of tubulin polymerization. The global Tetrahydrofurfuryl Bromide market was valued at US$ million in 2023 and is anticipated to reach US$ million by 2030, witnessing a CAGR of % during t.....
