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Bone Graft and Substitutes-Global Market Insights and Sales Trends 2025
Synopsis
Bone grafting is a surgical procedure that replaces missing bone with material from patient’s own body, an artificial, synthetic, or natural substitute. A bone substitute is a synthetic, inorganic or biologically organic combination which can be inserted for the treatment of a bone defect instead of autogenous or allogenous bone, Bone substitutes can be broadly categorized into bone grafts (autograft, allograft, xenograft), ceramics (hydroxyapatite, TCP, calcium sulphate) and growth factors (DBM, PRP, BMP’S).
The global Bone Graft and Substitutes market size is expected to reach US$ 3271.6 million by 2029, growing at a CAGR of 3.1% from 2023 to 2029. The market is mainly driven by the significant applications of Bone Graft and Substitutes in various end use industries. The expanding demands from the Spinal Fusion, Long Bone, Foot and Ankle and Craniomaxilofacial, are propelling Bone Graft and Substitutes market. Bone Grafts, one of the segments analysed in this report, is projected to record % CAGR and reach US$ million by the end of the analysis period. Growth in the Ceramics segment is estimated at % CAGR for the next seven-year period.
Asia Pacific shows high growth potential for Bone Graft and Substitutes market, driven by demand from China, the second largest economy with some signs of stabilising, the Bone Graft and Substitutes market in China is forecast to reach US$ million by 2029, trailing a CAGR of % over the 2023-2029 period, while the U.S. market will reach US$ million by 2029, exhibiting a CAGR of % during the same period.
Report Objectives
This report provides market insight on the different segments, by players, by Type, by Application. Market size and forecast (2018-2029) has been provided in the report. The primary objectives of this report are to provide 1) global market size and forecasts, growth rates, market dynamics, industry structure and developments, market situation, trends; 2) global market share and ranking by company; 3) comprehensive presentation of the global market for Bone Graft and Substitutes, with both quantitative and qualitative analysis through detailed segmentation; 4) detailed value chain analysis and review of growth factors essential for the existing market players and new entrants; 5) emerging opportunities in the market and the future impact of major drivers and restraints of the market.
Key Features of The Study:
This report provides in-depth analysis of the global Bone Graft and Substitutes market, and provides market size (US$ million) and CAGR for the forecast period (2023-2029), considering 2022 as the base year.
This report profiles key players in the global Bone Graft and Substitutes market based on the following parameters - company details (found date, headquarters, manufacturing bases), products portfolio, Bone Graft and Substitutes sales data, market share and ranking.
This report elucidates potential market opportunities across different segments and explains attractive investment proposition matrices for this market.
This report illustrates key insights about market drivers, restraints, opportunities, market trends, regional outlook.
Key companies of Bone Graft and Substitutes covered in this report include Medtronic, Zimmer Holding Inc., DePuy Synthes, Stryker, Geistlich Pharma AG, RTI Surgical, Inc., Dentsply Sirona, LifeNet Health and BioHorizons, etc.
The global Bone Graft and Substitutes market report caters to various stakeholders in this industry including investors, suppliers, product players, distributors, new entrants, and financial analysts.
Market Segmentation
Company Profiles:
Medtronic
Zimmer Holding Inc.
DePuy Synthes
Stryker
Geistlich Pharma AG
RTI Surgical, Inc.
Dentsply Sirona
LifeNet Health
BioHorizons
Orthogen, LLC
Dentium CO., LTD
Institut Straumann AG
Global Bone Graft and Substitutes market, by region:
North America (U.S., Canada, Mexico)
Europe (Germany, France, UK, Italy, etc.)
Asia Pacific (China, Japan, South Korea, Southeast Asia, India, etc.)
South America (Brazil, etc.)
Middle East and Africa (Turkey, GCC Countries, Africa, etc.)
Global Bone Graft and Substitutes market, Segment by Type:
Bone Grafts
Ceramics
Growth Factors
Global Bone Graft and Substitutes market, by Application
Spinal Fusion
Long Bone
Foot and Ankle
Craniomaxilofacial
Joint Reconstruction
Dental
Core Chapters
Chapter One: Introduces the report scope of the report, executive summary of global and regional market size and CAGR for the history and forecast period (2018-2023, 2024-2029). It offers a high-level view of the current state of the market and its likely evolution in the short to mid-term, and long term.
Chapter Two: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter Three: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter Four: Detailed analysis of Bone Graft and Substitutes companies’ competitive landscape, revenue, market share and ranking, latest development plan, merger, and acquisition information, etc.
Chapter Five: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product introduction, revenue, recent development, etc.
Chapter Six, Seven, Eight, Nine and Ten: North America, Europe, Asia Pacific, Latin America, Middle East & Africa, revenue by country.
Chapter Eleven: this section also introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by companies in the industry, and the analysis of relevant policies in the industry.
Chapter Twelve: Research Finding/Conclusion
Bone grafting is a surgical procedure that replaces missing bone with material from patient’s own body, an artificial, synthetic, or natural substitute. A bone substitute is a synthetic, inorganic or biologically organic combination which can be inserted for the treatment of a bone defect instead of autogenous or allogenous bone, Bone substitutes can be broadly categorized into bone grafts (autograft, allograft, xenograft), ceramics (hydroxyapatite, TCP, calcium sulphate) and growth factors (DBM, PRP, BMP’S).
The global Bone Graft and Substitutes market size is expected to reach US$ 3271.6 million by 2029, growing at a CAGR of 3.1% from 2023 to 2029. The market is mainly driven by the significant applications of Bone Graft and Substitutes in various end use industries. The expanding demands from the Spinal Fusion, Long Bone, Foot and Ankle and Craniomaxilofacial, are propelling Bone Graft and Substitutes market. Bone Grafts, one of the segments analysed in this report, is projected to record % CAGR and reach US$ million by the end of the analysis period. Growth in the Ceramics segment is estimated at % CAGR for the next seven-year period.
Asia Pacific shows high growth potential for Bone Graft and Substitutes market, driven by demand from China, the second largest economy with some signs of stabilising, the Bone Graft and Substitutes market in China is forecast to reach US$ million by 2029, trailing a CAGR of % over the 2023-2029 period, while the U.S. market will reach US$ million by 2029, exhibiting a CAGR of % during the same period.
Report Objectives
This report provides market insight on the different segments, by players, by Type, by Application. Market size and forecast (2018-2029) has been provided in the report. The primary objectives of this report are to provide 1) global market size and forecasts, growth rates, market dynamics, industry structure and developments, market situation, trends; 2) global market share and ranking by company; 3) comprehensive presentation of the global market for Bone Graft and Substitutes, with both quantitative and qualitative analysis through detailed segmentation; 4) detailed value chain analysis and review of growth factors essential for the existing market players and new entrants; 5) emerging opportunities in the market and the future impact of major drivers and restraints of the market.
Key Features of The Study:
This report provides in-depth analysis of the global Bone Graft and Substitutes market, and provides market size (US$ million) and CAGR for the forecast period (2023-2029), considering 2022 as the base year.
This report profiles key players in the global Bone Graft and Substitutes market based on the following parameters - company details (found date, headquarters, manufacturing bases), products portfolio, Bone Graft and Substitutes sales data, market share and ranking.
This report elucidates potential market opportunities across different segments and explains attractive investment proposition matrices for this market.
This report illustrates key insights about market drivers, restraints, opportunities, market trends, regional outlook.
Key companies of Bone Graft and Substitutes covered in this report include Medtronic, Zimmer Holding Inc., DePuy Synthes, Stryker, Geistlich Pharma AG, RTI Surgical, Inc., Dentsply Sirona, LifeNet Health and BioHorizons, etc.
The global Bone Graft and Substitutes market report caters to various stakeholders in this industry including investors, suppliers, product players, distributors, new entrants, and financial analysts.
Market Segmentation
Company Profiles:
Medtronic
Zimmer Holding Inc.
DePuy Synthes
Stryker
Geistlich Pharma AG
RTI Surgical, Inc.
Dentsply Sirona
LifeNet Health
BioHorizons
Orthogen, LLC
Dentium CO., LTD
Institut Straumann AG
Global Bone Graft and Substitutes market, by region:
North America (U.S., Canada, Mexico)
Europe (Germany, France, UK, Italy, etc.)
Asia Pacific (China, Japan, South Korea, Southeast Asia, India, etc.)
South America (Brazil, etc.)
Middle East and Africa (Turkey, GCC Countries, Africa, etc.)
Global Bone Graft and Substitutes market, Segment by Type:
Bone Grafts
Ceramics
Growth Factors
Global Bone Graft and Substitutes market, by Application
Spinal Fusion
Long Bone
Foot and Ankle
Craniomaxilofacial
Joint Reconstruction
Dental
Core Chapters
Chapter One: Introduces the report scope of the report, executive summary of global and regional market size and CAGR for the history and forecast period (2018-2023, 2024-2029). It offers a high-level view of the current state of the market and its likely evolution in the short to mid-term, and long term.
Chapter Two: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter Three: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter Four: Detailed analysis of Bone Graft and Substitutes companies’ competitive landscape, revenue, market share and ranking, latest development plan, merger, and acquisition information, etc.
Chapter Five: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product introduction, revenue, recent development, etc.
Chapter Six, Seven, Eight, Nine and Ten: North America, Europe, Asia Pacific, Latin America, Middle East & Africa, revenue by country.
Chapter Eleven: this section also introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by companies in the industry, and the analysis of relevant policies in the industry.
Chapter Twelve: Research Finding/Conclusion
Index1 Market Overview of Bone Graft and Substitutes
1.1 Bone Graft and Substitutes Market Overview
1.1.1 Bone Graft and Substitutes Product Scope
1.1.2 Bone Graft and Substitutes Market Status and Outlook
1.2 Global Bone Graft and Substitutes Market Size Overview by Region 2018 VS 2022 VS 2029
1.3 Global Bone Graft and Substitutes Market Size by Region (2018-2029)
1.4 Global Bone Graft and Substitutes Historic Market Size by Region (2018-2023)
1.5 Global Bone Graft and Substitutes Market Size Forecast by Region (2024-2029)
1.6 Key Regions, Bone Graft and Substitutes Market Size (2018-2029)
1.6.1 North America Bone Graft and Substitutes Market Size (2018-2029)
1.6.2 Europe Bone Graft and Substitutes Market Size (2018-2029)
1.6.3 Asia-Pacific Bone Graft and Substitutes Market Size (2018-2029)
1.6.4 Latin America Bone Graft and Substitutes Market Size (2018-2029)
1.6.5 Middle East & Africa Bone Graft and Substitutes Market Size (2018-2029)
2 Bone Graft and Substitutes Market by Type
2.1 Introduction
2.1.1 Bone Grafts
2.1.2 Ceramics
2.1.3 Growth Factors
2.2 Global Bone Graft and Substitutes Market Size by Type: 2018 VS 2022 VS 2029
2.2.1 Global Bone Graft and Substitutes Historic Market Size by Type (2018-2023)
2.2.2 Global Bone Graft and Substitutes Forecasted Market Size by Type (2024-2029)
2.3 Key Regions Market Size by Type
2.3.1 North America Bone Graft and Substitutes Revenue Breakdown by Type (2018-2029)
2.3.2 Europe Bone Graft and Substitutes Revenue Breakdown by Type (2018-2029)
2.3.3 Asia-Pacific Bone Graft and Substitutes Revenue Breakdown by Type (2018-2029)
2.3.4 Latin America Bone Graft and Substitutes Revenue Breakdown by Type (2018-2029)
2.3.5 Middle East and Africa Bone Graft and Substitutes Revenue Breakdown by Type (2018-2029)
3 Bone Graft and Substitutes Market Overview by Application
3.1 Introduction
3.1.1 Spinal Fusion
3.1.2 Long Bone
3.1.3 Foot and Ankle
3.1.4 Craniomaxilofacial
3.1.5 Joint Reconstruction
3.1.6 Dental
3.2 Global Bone Graft and Substitutes Market Size by Application: 2018 VS 2022 VS 2029
3.2.1 Global Bone Graft and Substitutes Historic Market Size by Application (2018-2023)
3.2.2 Global Bone Graft and Substitutes Forecasted Market Size by Application (2024-2029)
3.3 Key Regions Market Size by Application
3.3.1 North America Bone Graft and Substitutes Revenue Breakdown by Application (2018-2029)
3.3.2 Europe Bone Graft and Substitutes Revenue Breakdown by Application (2018-2029)
3.3.3 Asia-Pacific Bone Graft and Substitutes Revenue Breakdown by Application (2018-2029)
3.3.4 Latin America Bone Graft and Substitutes Revenue Breakdown by Application (2018-2029)
3.3.5 Middle East and Africa Bone Graft and Substitutes Revenue Breakdown by Application (2018-2029)
4 Bone Graft and Substitutes Competition Analysis by Players
4.1 Global Bone Graft and Substitutes Market Size by Players (2018-2023)
4.2 Global Top Players by Company Type (Tier 1, Tier 2 and Tier 3) & (based on the Revenue in Bone Graft and Substitutes as of 2022)
4.3 Date of Key Players Enter into Bone Graft and Substitutes Market
4.4 Global Top Players Bone Graft and Substitutes Headquarters and Area Served
4.5 Key Players Bone Graft and Substitutes Product Solution and Service
4.6 Competitive Status
4.6.1 Bone Graft and Substitutes Market Concentration Rate
4.6.2 Mergers & Acquisitions, Expansion Plans
5 Company (Top Players) Profiles
5.1 Medtronic
5.1.1 Medtronic Profile
5.1.2 Medtronic Main Business
5.1.3 Medtronic Bone Graft and Substitutes Products, Services and Solutions
5.1.4 Medtronic Bone Graft and Substitutes Revenue (US$ Million) & (2018-2023)
5.1.5 Medtronic Recent Developments
5.2 Zimmer Holding Inc.
5.2.1 Zimmer Holding Inc. Profile
5.2.2 Zimmer Holding Inc. Main Business
5.2.3 Zimmer Holding Inc. Bone Graft and Substitutes Products, Services and Solutions
5.2.4 Zimmer Holding Inc. Bone Graft and Substitutes Revenue (US$ Million) & (2018-2023)
5.2.5 Zimmer Holding Inc. Recent Developments
5.3 DePuy Synthes
5.3.1 DePuy Synthes Profile
5.3.2 DePuy Synthes Main Business
5.3.3 DePuy Synthes Bone Graft and Substitutes Products, Services and Solutions
5.3.4 DePuy Synthes Bone Graft and Substitutes Revenue (US$ Million) & (2018-2023)
5.3.5 Stryker Recent Developments
5.4 Stryker
5.4.1 Stryker Profile
5.4.2 Stryker Main Business
5.4.3 Stryker Bone Graft and Substitutes Products, Services and Solutions
5.4.4 Stryker Bone Graft and Substitutes Revenue (US$ Million) & (2018-2023)
5.4.5 Stryker Recent Developments
5.5 Geistlich Pharma AG
5.5.1 Geistlich Pharma AG Profile
5.5.2 Geistlich Pharma AG Main Business
5.5.3 Geistlich Pharma AG Bone Graft and Substitutes Products, Services and Solutions
5.5.4 Geistlich Pharma AG Bone Graft and Substitutes Revenue (US$ Million) & (2018-2023)
5.5.5 Geistlich Pharma AG Recent Developments
5.6 RTI Surgical, Inc.
5.6.1 RTI Surgical, Inc. Profile
5.6.2 RTI Surgical, Inc. Main Business
5.6.3 RTI Surgical, Inc. Bone Graft and Substitutes Products, Services and Solutions
5.6.4 RTI Surgical, Inc. Bone Graft and Substitutes Revenue (US$ Million) & (2018-2023)
5.6.5 RTI Surgical, Inc. Recent Developments
5.7 Dentsply Sirona
5.7.1 Dentsply Sirona Profile
5.7.2 Dentsply Sirona Main Business
5.7.3 Dentsply Sirona Bone Graft and Substitutes Products, Services and Solutions
5.7.4 Dentsply Sirona Bone Graft and Substitutes Revenue (US$ Million) & (2018-2023)
5.7.5 Dentsply Sirona Recent Developments
5.8 LifeNet Health
5.8.1 LifeNet Health Profile
5.8.2 LifeNet Health Main Business
5.8.3 LifeNet Health Bone Graft and Substitutes Products, Services and Solutions
5.8.4 LifeNet Health Bone Graft and Substitutes Revenue (US$ Million) & (2018-2023)
5.8.5 LifeNet Health Recent Developments
5.9 BioHorizons
5.9.1 BioHorizons Profile
5.9.2 BioHorizons Main Business
5.9.3 BioHorizons Bone Graft and Substitutes Products, Services and Solutions
5.9.4 BioHorizons Bone Graft and Substitutes Revenue (US$ Million) & (2018-2023)
5.9.5 BioHorizons Recent Developments
5.10 Orthogen, LLC
5.10.1 Orthogen, LLC Profile
5.10.2 Orthogen, LLC Main Business
5.10.3 Orthogen, LLC Bone Graft and Substitutes Products, Services and Solutions
5.10.4 Orthogen, LLC Bone Graft and Substitutes Revenue (US$ Million) & (2018-2023)
5.10.5 Orthogen, LLC Recent Developments
5.11 Dentium CO., LTD
5.11.1 Dentium CO., LTD Profile
5.11.2 Dentium CO., LTD Main Business
5.11.3 Dentium CO., LTD Bone Graft and Substitutes Products, Services and Solutions
5.11.4 Dentium CO., LTD Bone Graft and Substitutes Revenue (US$ Million) & (2018-2023)
5.11.5 Dentium CO., LTD Recent Developments
5.12 Institut Straumann AG
5.12.1 Institut Straumann AG Profile
5.12.2 Institut Straumann AG Main Business
5.12.3 Institut Straumann AG Bone Graft and Substitutes Products, Services and Solutions
5.12.4 Institut Straumann AG Bone Graft and Substitutes Revenue (US$ Million) & (2018-2023)
5.12.5 Institut Straumann AG Recent Developments
6 North America
6.1 North America Bone Graft and Substitutes Market Size by Country (2018-2029)
6.2 U.S.
6.3 Canada
7 Europe
7.1 Europe Bone Graft and Substitutes Market Size by Country (2018-2029)
7.2 Germany
7.3 France
7.4 U.K.
7.5 Italy
7.6 Russia
7.7 Nordic Countries
7.8 Rest of Europe
8 Asia-Pacific
8.1 Asia-Pacific Bone Graft and Substitutes Market Size by Region (2018-2029)
8.2 China
8.3 Japan
8.4 South Korea
8.5 Southeast Asia
8.6 India
8.7 Australia
8.8 Rest of Asia-Pacific
9 Latin America
9.1 Latin America Bone Graft and Substitutes Market Size by Country (2018-2029)
9.2 Mexico
9.3 Brazil
9.4 Rest of Latin America
10 Middle East & Africa
10.1 Middle East & Africa Bone Graft and Substitutes Market Size by Country (2018-2029)
10.2 Turkey
10.3 Saudi Arabia
10.4 UAE
10.5 Rest of Middle East & Africa
11 Bone Graft and Substitutes Market Dynamics
11.1 Bone Graft and Substitutes Industry Trends
11.2 Bone Graft and Substitutes Market Drivers
11.3 Bone Graft and Substitutes Market Challenges
11.4 Bone Graft and Substitutes Market Restraints
12 Research Finding /Conclusion
13 Methodology and Data Source
13.1 Methodology/Research Approach
13.1.1 Research Programs/Design
13.1.2 Market Size Estimation
13.1.3 Market Breakdown and Data Triangulation
13.2 Data Source
13.2.1 Secondary Sources
13.2.2 Primary Sources
13.3 Disclaimer
13.4 Author List
Published By : QY Research
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