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Global Plastic Demineralized Bone Fiber Market Research Report 2025
Synopsis
Demineralized bone matrix (DBM) is a form of allograft using acidic solution to remove mineral components, while leaving much of the proteinaceous components native to bone, with small amounts of calcium‐based solids, inorganic phosphates, and some trace cell debris. It is an osteoconductive and osteoinductive biomaterial and is approved as a medical device for use in bone defects and spinal fusion. To pack consistently into the defect sites and stay firmly in the filling parts, DBM products have various forms combined with biocompatible viscous carriers, including sponges, strips, injectable putty, paste, and paste infused with chips.
The most popular DBM product is a moldable bone paste or putty, which can be consistently packed into defect sites and remain firm. A moldable DBM product could be made of the composite of DBM powder/particles combined with biocompatible viscous carriers, which provides a stable suspension of DBM powder/particles. In general, according to their molecular weight, the viscous carriers could be divided into the following two classifications: (i) polymer materials, such as collagen, chitosan, hyaluronic acid (HA), carboxymethylcellulose (CMC), and poloxamer 407; and (ii) low molecular materials, such as glycerol, calcium sulfate, and bioactive glass .
The polymer carriers mainly include the natural polymer materials (e.g. chitosan, HA, sodium alginate, CMC, and type I collagen) and synthetic polymer materials (e.g. poloxamer 407). They are all demonstrated to be biocompatible and biodegradable after implantation in vivo, and have attractive viscidity to cohere with DBM powder particles.The low molecular carriers mainly include glycerol, calcium sulfate, and bioactive glass. They all have good plasticity, could be arbitrarily shaped mixed with DBM, and could help with osteogenesis due to their unique characteristics.
Global Plastic Demineralized Bone Fiber market is projected to reach US$ 929.1 million in 2029, increasing from US$ 620 million in 2022, with the CAGR of 4.6% during the period of 2023 to 2029. Influencing issues, such as economy environments, COVID-19 and Russia-Ukraine War, have led to great market fluctuations in the past few years and are considered comprehensively in the whole Plastic Demineralized Bone Fiber market research.
Bone reconstruction procedures pose enormous challenges to surgeons due to the dense nature of human bones and the possibility of complications arising as a result of non-acceptance of donor cells by the patient’s body. Demineralized bone matrix solutions have emerged as a promising redress to these challenges, as these products are allografts formed by using acidic solutions to remove mineral components while leaving the natural bone proteins intact.
While the traditional allogeneic bone grafting procedure is highly likely to result in rejection and infection, DBM is not limited by the graft amount as the natural content in the matrix is abundant, making it more probable for acceptance by the patient’s immune system. Further, DBM-based bone repairing solutions can also reduce the risk of complications of graft harvest from the donor site, as well as shorten the surgery and recovery time. These distinct benefits of DBM over conventional bone reconstruction treatments will ensure an enduring growth of the market.
Report Scope
This report, based on historical analysis (2018-2022) and forecast calculation (2023-2029), aims to help readers to get a comprehensive understanding of global Plastic Demineralized Bone Fiber market with multiple angles, which provides sufficient supports to readers’ strategy and decision making.
By Company
Zimmer Biomet
Medtronic
ZimVie
NuVasive
Curasan,Inc.
DePuy Synthes (Johnson & Johnson)
Surgalign
Stryker
LifeNet Health
AlloSource
Medline Industries
Isto Biologics
AcuPure Fiber
CONMED Corporation
Tissue Regenix
Segment by Type
Polymer Materials
Low Molecular Materials
Segment by Application
Plastic Surgery
Spine Surgery
General Surgery
Reconstructive Surgery
Consumption by Region
North America
United States
Canada
Europe
Germany
France
U.K.
Italy
Russia
Asia-Pacific
China
Japan
South Korea
India
Australia
China Taiwan
Southeast Asia
Latin America
Mexico
Brazil
Argentina
Colombia
Middle East & Africa
Turkey
Saudi Arabia
UAE
The Plastic Demineralized Bone Fiber report covers below items:
Chapter 1: Product Basic Information (Definition, Type and Application)
Chapter 2: Manufacturers’ Competition Patterns
Chapter 3: Country Level Sales Analysis
Chapter 4: Product Type Analysis
Chapter 5: Product Application Analysis
Chapter 6: Manufacturers’ Outline
Chapter 7: Industry Chain, Market Channel and Customer Analysis
Chapter 8: Market Opportunities and Challenges
Chapter 9: Market Conclusions
Chapter 10: Research Methodology and Data Source
Demineralized bone matrix (DBM) is a form of allograft using acidic solution to remove mineral components, while leaving much of the proteinaceous components native to bone, with small amounts of calcium‐based solids, inorganic phosphates, and some trace cell debris. It is an osteoconductive and osteoinductive biomaterial and is approved as a medical device for use in bone defects and spinal fusion. To pack consistently into the defect sites and stay firmly in the filling parts, DBM products have various forms combined with biocompatible viscous carriers, including sponges, strips, injectable putty, paste, and paste infused with chips.
The most popular DBM product is a moldable bone paste or putty, which can be consistently packed into defect sites and remain firm. A moldable DBM product could be made of the composite of DBM powder/particles combined with biocompatible viscous carriers, which provides a stable suspension of DBM powder/particles. In general, according to their molecular weight, the viscous carriers could be divided into the following two classifications: (i) polymer materials, such as collagen, chitosan, hyaluronic acid (HA), carboxymethylcellulose (CMC), and poloxamer 407; and (ii) low molecular materials, such as glycerol, calcium sulfate, and bioactive glass .
The polymer carriers mainly include the natural polymer materials (e.g. chitosan, HA, sodium alginate, CMC, and type I collagen) and synthetic polymer materials (e.g. poloxamer 407). They are all demonstrated to be biocompatible and biodegradable after implantation in vivo, and have attractive viscidity to cohere with DBM powder particles.The low molecular carriers mainly include glycerol, calcium sulfate, and bioactive glass. They all have good plasticity, could be arbitrarily shaped mixed with DBM, and could help with osteogenesis due to their unique characteristics.
Global Plastic Demineralized Bone Fiber market is projected to reach US$ 929.1 million in 2029, increasing from US$ 620 million in 2022, with the CAGR of 4.6% during the period of 2023 to 2029. Influencing issues, such as economy environments, COVID-19 and Russia-Ukraine War, have led to great market fluctuations in the past few years and are considered comprehensively in the whole Plastic Demineralized Bone Fiber market research.
Bone reconstruction procedures pose enormous challenges to surgeons due to the dense nature of human bones and the possibility of complications arising as a result of non-acceptance of donor cells by the patient’s body. Demineralized bone matrix solutions have emerged as a promising redress to these challenges, as these products are allografts formed by using acidic solutions to remove mineral components while leaving the natural bone proteins intact.
While the traditional allogeneic bone grafting procedure is highly likely to result in rejection and infection, DBM is not limited by the graft amount as the natural content in the matrix is abundant, making it more probable for acceptance by the patient’s immune system. Further, DBM-based bone repairing solutions can also reduce the risk of complications of graft harvest from the donor site, as well as shorten the surgery and recovery time. These distinct benefits of DBM over conventional bone reconstruction treatments will ensure an enduring growth of the market.
Report Scope
This report, based on historical analysis (2018-2022) and forecast calculation (2023-2029), aims to help readers to get a comprehensive understanding of global Plastic Demineralized Bone Fiber market with multiple angles, which provides sufficient supports to readers’ strategy and decision making.
By Company
Zimmer Biomet
Medtronic
ZimVie
NuVasive
Curasan,Inc.
DePuy Synthes (Johnson & Johnson)
Surgalign
Stryker
LifeNet Health
AlloSource
Medline Industries
Isto Biologics
AcuPure Fiber
CONMED Corporation
Tissue Regenix
Segment by Type
Polymer Materials
Low Molecular Materials
Segment by Application
Plastic Surgery
Spine Surgery
General Surgery
Reconstructive Surgery
Consumption by Region
North America
United States
Canada
Europe
Germany
France
U.K.
Italy
Russia
Asia-Pacific
China
Japan
South Korea
India
Australia
China Taiwan
Southeast Asia
Latin America
Mexico
Brazil
Argentina
Colombia
Middle East & Africa
Turkey
Saudi Arabia
UAE
The Plastic Demineralized Bone Fiber report covers below items:
Chapter 1: Product Basic Information (Definition, Type and Application)
Chapter 2: Manufacturers’ Competition Patterns
Chapter 3: Country Level Sales Analysis
Chapter 4: Product Type Analysis
Chapter 5: Product Application Analysis
Chapter 6: Manufacturers’ Outline
Chapter 7: Industry Chain, Market Channel and Customer Analysis
Chapter 8: Market Opportunities and Challenges
Chapter 9: Market Conclusions
Chapter 10: Research Methodology and Data Source
Index1 Plastic Demineralized Bone Fiber Market Overview
1.1 Product Overview and Scope of Plastic Demineralized Bone Fiber
1.2 Plastic Demineralized Bone Fiber Segment by Type
1.2.1 Global Plastic Demineralized Bone Fiber Market Value Comparison by Type (2023-2029)
1.2.2 Polymer Materials
1.2.3 Low Molecular Materials
1.3 Plastic Demineralized Bone Fiber Segment by Application
1.3.1 Global Plastic Demineralized Bone Fiber Market Value by Application: (2023-2029)
1.3.2 Plastic Surgery
1.3.3 Spine Surgery
1.3.4 General Surgery
1.3.5 Reconstructive Surgery
1.4 Global Plastic Demineralized Bone Fiber Market Size Estimates and Forecasts
1.4.1 Global Plastic Demineralized Bone Fiber Revenue 2018-2029
1.4.2 Global Plastic Demineralized Bone Fiber Sales 2018-2029
1.4.3 Global Plastic Demineralized Bone Fiber Market Average Price (2018-2029)
1.5 Assumptions and Limitations
2 Plastic Demineralized Bone Fiber Market Competition by Manufacturers
2.1 Global Plastic Demineralized Bone Fiber Sales Market Share by Manufacturers (2018-2023)
2.2 Global Plastic Demineralized Bone Fiber Revenue Market Share by Manufacturers (2018-2023)
2.3 Global Plastic Demineralized Bone Fiber Average Price by Manufacturers (2018-2023)
2.4 Global Plastic Demineralized Bone Fiber Industry Ranking 2021 VS 2022 VS 2023
2.5 Global Key Manufacturers of Plastic Demineralized Bone Fiber, Manufacturing Sites & Headquarters
2.6 Global Key Manufacturers of Plastic Demineralized Bone Fiber, Product Type & Application
2.7 Plastic Demineralized Bone Fiber Market Competitive Situation and Trends
2.7.1 Plastic Demineralized Bone Fiber Market Concentration Rate
2.7.2 The Global Top 5 and Top 10 Largest Plastic Demineralized Bone Fiber Players Market Share by Revenue
2.7.3 Global Plastic Demineralized Bone Fiber Market Share by Company Type (Tier 1, Tier 2 and Tier 3)
2.8 Manufacturers Mergers & Acquisitions, Expansion Plans
3 Plastic Demineralized Bone Fiber Retrospective Market Scenario by Region
3.1 Global Plastic Demineralized Bone Fiber Market Size by Region: 2018 Versus 2022 Versus 2029
3.2 Global Plastic Demineralized Bone Fiber Global Plastic Demineralized Bone Fiber Sales by Region: 2018-2029
3.2.1 Global Plastic Demineralized Bone Fiber Sales by Region: 2018-2023
3.2.2 Global Plastic Demineralized Bone Fiber Sales by Region: 2024-2029
3.3 Global Plastic Demineralized Bone Fiber Global Plastic Demineralized Bone Fiber Revenue by Region: 2018-2029
3.3.1 Global Plastic Demineralized Bone Fiber Revenue by Region: 2018-2023
3.3.2 Global Plastic Demineralized Bone Fiber Revenue by Region: 2024-2029
3.4 North America Plastic Demineralized Bone Fiber Market Facts & Figures by Country
3.4.1 North America Plastic Demineralized Bone Fiber Market Size by Country: 2018 VS 2022 VS 2029
3.4.2 North America Plastic Demineralized Bone Fiber Sales by Country (2018-2029)
3.4.3 North America Plastic Demineralized Bone Fiber Revenue by Country (2018-2029)
3.4.4 United States
3.4.5 Canada
3.5 Europe Plastic Demineralized Bone Fiber Market Facts & Figures by Country
3.5.1 Europe Plastic Demineralized Bone Fiber Market Size by Country: 2018 VS 2022 VS 2029
3.5.2 Europe Plastic Demineralized Bone Fiber Sales by Country (2018-2029)
3.5.3 Europe Plastic Demineralized Bone Fiber Revenue by Country (2018-2029)
3.5.4 Germany
3.5.5 France
3.5.6 U.K.
3.5.7 Italy
3.5.8 Russia
3.6 Asia Pacific Plastic Demineralized Bone Fiber Market Facts & Figures by Country
3.6.1 Asia Pacific Plastic Demineralized Bone Fiber Market Size by Country: 2018 VS 2022 VS 2029
3.6.2 Asia Pacific Plastic Demineralized Bone Fiber Sales by Country (2018-2029)
3.6.3 Asia Pacific Plastic Demineralized Bone Fiber Revenue by Country (2018-2029)
3.6.4 China
3.6.5 Japan
3.6.6 South Korea
3.6.7 India
3.6.8 Australia
3.6.9 China Taiwan
3.6.10 Southeast Asia
3.7 Latin America Plastic Demineralized Bone Fiber Market Facts & Figures by Country
3.7.1 Latin America Plastic Demineralized Bone Fiber Market Size by Country: 2018 VS 2022 VS 2029
3.7.2 Latin America Plastic Demineralized Bone Fiber Sales by Country (2018-2029)
3.7.3 Latin America Plastic Demineralized Bone Fiber Revenue by Country (2018-2029)
3.7.4 Mexico
3.7.5 Brazil
3.7.6 Argentina
3.7.7 Colombia
3.8 Middle East and Africa Plastic Demineralized Bone Fiber Market Facts & Figures by Country
3.8.1 Middle East and Africa Plastic Demineralized Bone Fiber Market Size by Country: 2018 VS 2022 VS 2029
3.8.2 Middle East and Africa Plastic Demineralized Bone Fiber Sales by Country (2018-2029)
3.8.3 Middle East and Africa Plastic Demineralized Bone Fiber Revenue by Country (2018-2029)
3.8.4 Turkey
3.8.5 Saudi Arabia
3.8.6 UAE
4 Segment by Type
4.1 Global Plastic Demineralized Bone Fiber Sales by Type (2018-2029)
4.1.1 Global Plastic Demineralized Bone Fiber Sales by Type (2018-2023)
4.1.2 Global Plastic Demineralized Bone Fiber Sales by Type (2024-2029)
4.1.3 Global Plastic Demineralized Bone Fiber Sales Market Share by Type (2018-2029)
4.2 Global Plastic Demineralized Bone Fiber Revenue by Type (2018-2029)
4.2.1 Global Plastic Demineralized Bone Fiber Revenue by Type (2018-2023)
4.2.2 Global Plastic Demineralized Bone Fiber Revenue by Type (2024-2029)
4.2.3 Global Plastic Demineralized Bone Fiber Revenue Market Share by Type (2018-2029)
4.3 Global Plastic Demineralized Bone Fiber Price by Type (2018-2029)
5 Segment by Application
5.1 Global Plastic Demineralized Bone Fiber Sales by Application (2018-2029)
5.1.1 Global Plastic Demineralized Bone Fiber Sales by Application (2018-2023)
5.1.2 Global Plastic Demineralized Bone Fiber Sales by Application (2024-2029)
5.1.3 Global Plastic Demineralized Bone Fiber Sales Market Share by Application (2018-2029)
5.2 Global Plastic Demineralized Bone Fiber Revenue by Application (2018-2029)
5.2.1 Global Plastic Demineralized Bone Fiber Revenue by Application (2018-2023)
5.2.2 Global Plastic Demineralized Bone Fiber Revenue by Application (2024-2029)
5.2.3 Global Plastic Demineralized Bone Fiber Revenue Market Share by Application (2018-2029)
5.3 Global Plastic Demineralized Bone Fiber Price by Application (2018-2029)
6 Key Companies Profiled
6.1 Zimmer Biomet
6.1.1 Zimmer Biomet Corporation Information
6.1.2 Zimmer Biomet Description and Business Overview
6.1.3 Zimmer Biomet Plastic Demineralized Bone Fiber Sales, Revenue and Gross Margin (2018-2023)
6.1.4 Zimmer Biomet Plastic Demineralized Bone Fiber Product Portfolio
6.1.5 Zimmer Biomet Recent Developments/Updates
6.2 Medtronic
6.2.1 Medtronic Corporation Information
6.2.2 Medtronic Description and Business Overview
6.2.3 Medtronic Plastic Demineralized Bone Fiber Sales, Revenue and Gross Margin (2018-2023)
6.2.4 Medtronic Plastic Demineralized Bone Fiber Product Portfolio
6.2.5 Medtronic Recent Developments/Updates
6.3 ZimVie
6.3.1 ZimVie Corporation Information
6.3.2 ZimVie Description and Business Overview
6.3.3 ZimVie Plastic Demineralized Bone Fiber Sales, Revenue and Gross Margin (2018-2023)
6.3.4 ZimVie Plastic Demineralized Bone Fiber Product Portfolio
6.3.5 ZimVie Recent Developments/Updates
6.4 NuVasive
6.4.1 NuVasive Corporation Information
6.4.2 NuVasive Description and Business Overview
6.4.3 NuVasive Plastic Demineralized Bone Fiber Sales, Revenue and Gross Margin (2018-2023)
6.4.4 NuVasive Plastic Demineralized Bone Fiber Product Portfolio
6.4.5 NuVasive Recent Developments/Updates
6.5 Curasan,Inc.
6.5.1 Curasan,Inc. Corporation Information
6.5.2 Curasan,Inc. Description and Business Overview
6.5.3 Curasan,Inc. Plastic Demineralized Bone Fiber Sales, Revenue and Gross Margin (2018-2023)
6.5.4 Curasan,Inc. Plastic Demineralized Bone Fiber Product Portfolio
6.5.5 Curasan,Inc. Recent Developments/Updates
6.6 DePuy Synthes (Johnson & Johnson)
6.6.1 DePuy Synthes (Johnson & Johnson) Corporation Information
6.6.2 DePuy Synthes (Johnson & Johnson) Description and Business Overview
6.6.3 DePuy Synthes (Johnson & Johnson) Plastic Demineralized Bone Fiber Sales, Revenue and Gross Margin (2018-2023)
6.6.4 DePuy Synthes (Johnson & Johnson) Plastic Demineralized Bone Fiber Product Portfolio
6.6.5 DePuy Synthes (Johnson & Johnson) Recent Developments/Updates
6.7 Surgalign
6.6.1 Surgalign Corporation Information
6.6.2 Surgalign Description and Business Overview
6.6.3 Surgalign Plastic Demineralized Bone Fiber Sales, Revenue and Gross Margin (2018-2023)
6.4.4 Surgalign Plastic Demineralized Bone Fiber Product Portfolio
6.7.5 Surgalign Recent Developments/Updates
6.8 Stryker
6.8.1 Stryker Corporation Information
6.8.2 Stryker Description and Business Overview
6.8.3 Stryker Plastic Demineralized Bone Fiber Sales, Revenue and Gross Margin (2018-2023)
6.8.4 Stryker Plastic Demineralized Bone Fiber Product Portfolio
6.8.5 Stryker Recent Developments/Updates
6.9 LifeNet Health
6.9.1 LifeNet Health Corporation Information
6.9.2 LifeNet Health Description and Business Overview
6.9.3 LifeNet Health Plastic Demineralized Bone Fiber Sales, Revenue and Gross Margin (2018-2023)
6.9.4 LifeNet Health Plastic Demineralized Bone Fiber Product Portfolio
6.9.5 LifeNet Health Recent Developments/Updates
6.10 AlloSource
6.10.1 AlloSource Corporation Information
6.10.2 AlloSource Description and Business Overview
6.10.3 AlloSource Plastic Demineralized Bone Fiber Sales, Revenue and Gross Margin (2018-2023)
6.10.4 AlloSource Plastic Demineralized Bone Fiber Product Portfolio
6.10.5 AlloSource Recent Developments/Updates
6.11 Medline Industries
6.11.1 Medline Industries Corporation Information
6.11.2 Medline Industries Plastic Demineralized Bone Fiber Description and Business Overview
6.11.3 Medline Industries Plastic Demineralized Bone Fiber Sales, Revenue and Gross Margin (2018-2023)
6.11.4 Medline Industries Plastic Demineralized Bone Fiber Product Portfolio
6.11.5 Medline Industries Recent Developments/Updates
6.12 Isto Biologics
6.12.1 Isto Biologics Corporation Information
6.12.2 Isto Biologics Plastic Demineralized Bone Fiber Description and Business Overview
6.12.3 Isto Biologics Plastic Demineralized Bone Fiber Sales, Revenue and Gross Margin (2018-2023)
6.12.4 Isto Biologics Plastic Demineralized Bone Fiber Product Portfolio
6.12.5 Isto Biologics Recent Developments/Updates
6.13 AcuPure Fiber
6.13.1 AcuPure Fiber Corporation Information
6.13.2 AcuPure Fiber Plastic Demineralized Bone Fiber Description and Business Overview
6.13.3 AcuPure Fiber Plastic Demineralized Bone Fiber Sales, Revenue and Gross Margin (2018-2023)
6.13.4 AcuPure Fiber Plastic Demineralized Bone Fiber Product Portfolio
6.13.5 AcuPure Fiber Recent Developments/Updates
6.14 CONMED Corporation
6.14.1 CONMED Corporation Corporation Information
6.14.2 CONMED Corporation Plastic Demineralized Bone Fiber Description and Business Overview
6.14.3 CONMED Corporation Plastic Demineralized Bone Fiber Sales, Revenue and Gross Margin (2018-2023)
6.14.4 CONMED Corporation Plastic Demineralized Bone Fiber Product Portfolio
6.14.5 CONMED Corporation Recent Developments/Updates
6.15 Tissue Regenix
6.15.1 Tissue Regenix Corporation Information
6.15.2 Tissue Regenix Plastic Demineralized Bone Fiber Description and Business Overview
6.15.3 Tissue Regenix Plastic Demineralized Bone Fiber Sales, Revenue and Gross Margin (2018-2023)
6.15.4 Tissue Regenix Plastic Demineralized Bone Fiber Product Portfolio
6.15.5 Tissue Regenix Recent Developments/Updates
7 Industry Chain and Sales Channels Analysis
7.1 Plastic Demineralized Bone Fiber Industry Chain Analysis
7.2 Plastic Demineralized Bone Fiber Key Raw Materials
7.2.1 Key Raw Materials
7.2.2 Raw Materials Key Suppliers
7.3 Plastic Demineralized Bone Fiber Production Mode & Process
7.4 Plastic Demineralized Bone Fiber Sales and Marketing
7.4.1 Plastic Demineralized Bone Fiber Sales Channels
7.4.2 Plastic Demineralized Bone Fiber Distributors
7.5 Plastic Demineralized Bone Fiber Customers
8 Plastic Demineralized Bone Fiber Market Dynamics
8.1 Plastic Demineralized Bone Fiber Industry Trends
8.2 Plastic Demineralized Bone Fiber Market Drivers
8.3 Plastic Demineralized Bone Fiber Market Challenges
8.4 Plastic Demineralized Bone Fiber Market Restraints
9 Research Finding and Conclusion
10 Methodology and Data Source
10.1 Methodology/Research Approach
10.1.1 Research Programs/Design
10.1.2 Market Size Estimation
10.1.3 Market Breakdown and Data Triangulation
10.2 Data Source
10.2.1 Secondary Sources
10.2.2 Primary Sources
10.3 Author List
10.4 Disclaimer
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