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Global Small Molecule API and Intermediates Market Research Report 2025
Synopsis
Small-molecule APIs refer to drug molecules with relatively small chemical structures, which are often used to prepare active ingredients of pharmaceuticals. They are usually synthesized by organic synthesis methods, have clear chemical structures and activities, and can enter the human body through pharmaceutical preparations and exert therapeutic effects. Intermediates are intermediate compounds produced during the synthesis of small molecule APIs. They are important chemical intermediates connecting different steps of the synthetic pathway, and the final small molecule APIs are gradually synthesized through a series of chemical reactions. The synthesis and purification of intermediates is a key step in the drug synthesis process, ensuring the high efficiency, selectivity and yield of the synthetic route.
Global Small Molecule API and Intermediates market is projected to reach US$ million in 2029, increasing from US$ million in 2022, with the CAGR of % during the period of 2023 to 2029. Influencing issues, such as economy environments, COVID-19 and Russia-Ukraine War, have led to great market fluctuations in the past few years and are considered comprehensively in the whole Small Molecule API and Intermediates market research.
Small molecule APIs and intermediates play an important role in drug development and manufacturing. Small-molecule APIs are the active ingredients of drugs and have biological activity to treat target diseases. After they are synthesized, purified and formed into pharmaceutical preparations, they can be absorbed and utilized by the human body through oral administration, injection and other routes. Intermediates are precursors of small-molecule APIs that are transformed into final drugs through successive synthetic steps. The selection and optimization of intermediates is crucial to the efficiency and economy of the entire synthetic route. Small molecule APIs and intermediates are an integral part of drug development and manufacturing. By optimizing and controlling its synthesis and purification process, high-quality, high-efficiency, and safe drug products can be obtained, providing effective treatments for human health.
Report Scope
This report, based on historical analysis (2018-2022) and forecast calculation (2023-2029), aims to help readers to get a comprehensive understanding of global Small Molecule API and Intermediates market with multiple angles, which provides sufficient supports to readers’ strategy and decision making.
By Company
Asymchem
Cipla
Merck
Aurobindo Pharma
Teva Pharmaceutical Industries
Viatris
Bristol-Myers Squibb
Boehringer Ingelheim International
AbbVie
Sun Pharmaceutical Industries
Dr. Reddy's Laboratories
Albermarle Corporation
Cytovance Biologics
Zhejiang Ausun Pharmaceutical
Zhejiang Jiuzhou Pharmaceutical
Shenzhen BORUI Pharmaceutical Technology
Shanghai Haoyuan Chemexpress
Hangzhou Xinqiao Biotechnology
Segment by Type
API
Intermediate
Segment by Application
Clinical Treatment
Medical Research
Consumption by Region
North America
United States
Canada
Europe
Germany
France
U.K.
Italy
Russia
Asia-Pacific
China
Japan
South Korea
India
Australia
China Taiwan
Southeast Asia
Latin America
Mexico
Brazil
Argentina
Colombia
Middle East & Africa
Turkey
Saudi Arabia
UAE
The Small Molecule API and Intermediates report covers below items:
Chapter 1: Product Basic Information (Definition, Type and Application)
Chapter 2: Manufacturers’ Competition Patterns
Chapter 3: Country Level Sales Analysis
Chapter 4: Product Type Analysis
Chapter 5: Product Application Analysis
Chapter 6: Manufacturers’ Outline
Chapter 7: Industry Chain, Market Channel and Customer Analysis
Chapter 8: Market Opportunities and Challenges
Chapter 9: Market Conclusions
Chapter 10: Research Methodology and Data Source
Small-molecule APIs refer to drug molecules with relatively small chemical structures, which are often used to prepare active ingredients of pharmaceuticals. They are usually synthesized by organic synthesis methods, have clear chemical structures and activities, and can enter the human body through pharmaceutical preparations and exert therapeutic effects. Intermediates are intermediate compounds produced during the synthesis of small molecule APIs. They are important chemical intermediates connecting different steps of the synthetic pathway, and the final small molecule APIs are gradually synthesized through a series of chemical reactions. The synthesis and purification of intermediates is a key step in the drug synthesis process, ensuring the high efficiency, selectivity and yield of the synthetic route.
Global Small Molecule API and Intermediates market is projected to reach US$ million in 2029, increasing from US$ million in 2022, with the CAGR of % during the period of 2023 to 2029. Influencing issues, such as economy environments, COVID-19 and Russia-Ukraine War, have led to great market fluctuations in the past few years and are considered comprehensively in the whole Small Molecule API and Intermediates market research.
Small molecule APIs and intermediates play an important role in drug development and manufacturing. Small-molecule APIs are the active ingredients of drugs and have biological activity to treat target diseases. After they are synthesized, purified and formed into pharmaceutical preparations, they can be absorbed and utilized by the human body through oral administration, injection and other routes. Intermediates are precursors of small-molecule APIs that are transformed into final drugs through successive synthetic steps. The selection and optimization of intermediates is crucial to the efficiency and economy of the entire synthetic route. Small molecule APIs and intermediates are an integral part of drug development and manufacturing. By optimizing and controlling its synthesis and purification process, high-quality, high-efficiency, and safe drug products can be obtained, providing effective treatments for human health.
Report Scope
This report, based on historical analysis (2018-2022) and forecast calculation (2023-2029), aims to help readers to get a comprehensive understanding of global Small Molecule API and Intermediates market with multiple angles, which provides sufficient supports to readers’ strategy and decision making.
By Company
Asymchem
Cipla
Merck
Aurobindo Pharma
Teva Pharmaceutical Industries
Viatris
Bristol-Myers Squibb
Boehringer Ingelheim International
AbbVie
Sun Pharmaceutical Industries
Dr. Reddy's Laboratories
Albermarle Corporation
Cytovance Biologics
Zhejiang Ausun Pharmaceutical
Zhejiang Jiuzhou Pharmaceutical
Shenzhen BORUI Pharmaceutical Technology
Shanghai Haoyuan Chemexpress
Hangzhou Xinqiao Biotechnology
Segment by Type
API
Intermediate
Segment by Application
Clinical Treatment
Medical Research
Consumption by Region
North America
United States
Canada
Europe
Germany
France
U.K.
Italy
Russia
Asia-Pacific
China
Japan
South Korea
India
Australia
China Taiwan
Southeast Asia
Latin America
Mexico
Brazil
Argentina
Colombia
Middle East & Africa
Turkey
Saudi Arabia
UAE
The Small Molecule API and Intermediates report covers below items:
Chapter 1: Product Basic Information (Definition, Type and Application)
Chapter 2: Manufacturers’ Competition Patterns
Chapter 3: Country Level Sales Analysis
Chapter 4: Product Type Analysis
Chapter 5: Product Application Analysis
Chapter 6: Manufacturers’ Outline
Chapter 7: Industry Chain, Market Channel and Customer Analysis
Chapter 8: Market Opportunities and Challenges
Chapter 9: Market Conclusions
Chapter 10: Research Methodology and Data Source
Index1 Small Molecule API and Intermediates Market Overview
1.1 Product Overview and Scope of Small Molecule API and Intermediates
1.2 Small Molecule API and Intermediates Segment by Type
1.2.1 Global Small Molecule API and Intermediates Market Value Comparison by Type (2023-2029)
1.2.2 API
1.2.3 Intermediate
1.3 Small Molecule API and Intermediates Segment by Application
1.3.1 Global Small Molecule API and Intermediates Market Value by Application: (2023-2029)
1.3.2 Clinical Treatment
1.3.3 Medical Research
1.4 Global Small Molecule API and Intermediates Market Size Estimates and Forecasts
1.4.1 Global Small Molecule API and Intermediates Revenue 2018-2029
1.4.2 Global Small Molecule API and Intermediates Sales 2018-2029
1.4.3 Global Small Molecule API and Intermediates Market Average Price (2018-2029)
1.5 Assumptions and Limitations
2 Small Molecule API and Intermediates Market Competition by Manufacturers
2.1 Global Small Molecule API and Intermediates Sales Market Share by Manufacturers (2018-2023)
2.2 Global Small Molecule API and Intermediates Revenue Market Share by Manufacturers (2018-2023)
2.3 Global Small Molecule API and Intermediates Average Price by Manufacturers (2018-2023)
2.4 Global Small Molecule API and Intermediates Industry Ranking 2021 VS 2022 VS 2023
2.5 Global Key Manufacturers of Small Molecule API and Intermediates, Manufacturing Sites & Headquarters
2.6 Global Key Manufacturers of Small Molecule API and Intermediates, Product Type & Application
2.7 Small Molecule API and Intermediates Market Competitive Situation and Trends
2.7.1 Small Molecule API and Intermediates Market Concentration Rate
2.7.2 The Global Top 5 and Top 10 Largest Small Molecule API and Intermediates Players Market Share by Revenue
2.7.3 Global Small Molecule API and Intermediates Market Share by Company Type (Tier 1, Tier 2 and Tier 3)
2.8 Manufacturers Mergers & Acquisitions, Expansion Plans
3 Small Molecule API and Intermediates Retrospective Market Scenario by Region
3.1 Global Small Molecule API and Intermediates Market Size by Region: 2018 Versus 2022 Versus 2029
3.2 Global Small Molecule API and Intermediates Global Small Molecule API and Intermediates Sales by Region: 2018-2029
3.2.1 Global Small Molecule API and Intermediates Sales by Region: 2018-2023
3.2.2 Global Small Molecule API and Intermediates Sales by Region: 2024-2029
3.3 Global Small Molecule API and Intermediates Global Small Molecule API and Intermediates Revenue by Region: 2018-2029
3.3.1 Global Small Molecule API and Intermediates Revenue by Region: 2018-2023
3.3.2 Global Small Molecule API and Intermediates Revenue by Region: 2024-2029
3.4 North America Small Molecule API and Intermediates Market Facts & Figures by Country
3.4.1 North America Small Molecule API and Intermediates Market Size by Country: 2018 VS 2022 VS 2029
3.4.2 North America Small Molecule API and Intermediates Sales by Country (2018-2029)
3.4.3 North America Small Molecule API and Intermediates Revenue by Country (2018-2029)
3.4.4 United States
3.4.5 Canada
3.5 Europe Small Molecule API and Intermediates Market Facts & Figures by Country
3.5.1 Europe Small Molecule API and Intermediates Market Size by Country: 2018 VS 2022 VS 2029
3.5.2 Europe Small Molecule API and Intermediates Sales by Country (2018-2029)
3.5.3 Europe Small Molecule API and Intermediates Revenue by Country (2018-2029)
3.5.4 Germany
3.5.5 France
3.5.6 U.K.
3.5.7 Italy
3.5.8 Russia
3.6 Asia Pacific Small Molecule API and Intermediates Market Facts & Figures by Country
3.6.1 Asia Pacific Small Molecule API and Intermediates Market Size by Country: 2018 VS 2022 VS 2029
3.6.2 Asia Pacific Small Molecule API and Intermediates Sales by Country (2018-2029)
3.6.3 Asia Pacific Small Molecule API and Intermediates Revenue by Country (2018-2029)
3.6.4 China
3.6.5 Japan
3.6.6 South Korea
3.6.7 India
3.6.8 Australia
3.6.9 China Taiwan
3.6.10 Southeast Asia
3.7 Latin America Small Molecule API and Intermediates Market Facts & Figures by Country
3.7.1 Latin America Small Molecule API and Intermediates Market Size by Country: 2018 VS 2022 VS 2029
3.7.2 Latin America Small Molecule API and Intermediates Sales by Country (2018-2029)
3.7.3 Latin America Small Molecule API and Intermediates Revenue by Country (2018-2029)
3.7.4 Mexico
3.7.5 Brazil
3.7.6 Argentina
3.7.7 Colombia
3.8 Middle East and Africa Small Molecule API and Intermediates Market Facts & Figures by Country
3.8.1 Middle East and Africa Small Molecule API and Intermediates Market Size by Country: 2018 VS 2022 VS 2029
3.8.2 Middle East and Africa Small Molecule API and Intermediates Sales by Country (2018-2029)
3.8.3 Middle East and Africa Small Molecule API and Intermediates Revenue by Country (2018-2029)
3.8.4 Turkey
3.8.5 Saudi Arabia
3.8.6 UAE
4 Segment by Type
4.1 Global Small Molecule API and Intermediates Sales by Type (2018-2029)
4.1.1 Global Small Molecule API and Intermediates Sales by Type (2018-2023)
4.1.2 Global Small Molecule API and Intermediates Sales by Type (2024-2029)
4.1.3 Global Small Molecule API and Intermediates Sales Market Share by Type (2018-2029)
4.2 Global Small Molecule API and Intermediates Revenue by Type (2018-2029)
4.2.1 Global Small Molecule API and Intermediates Revenue by Type (2018-2023)
4.2.2 Global Small Molecule API and Intermediates Revenue by Type (2024-2029)
4.2.3 Global Small Molecule API and Intermediates Revenue Market Share by Type (2018-2029)
4.3 Global Small Molecule API and Intermediates Price by Type (2018-2029)
5 Segment by Application
5.1 Global Small Molecule API and Intermediates Sales by Application (2018-2029)
5.1.1 Global Small Molecule API and Intermediates Sales by Application (2018-2023)
5.1.2 Global Small Molecule API and Intermediates Sales by Application (2024-2029)
5.1.3 Global Small Molecule API and Intermediates Sales Market Share by Application (2018-2029)
5.2 Global Small Molecule API and Intermediates Revenue by Application (2018-2029)
5.2.1 Global Small Molecule API and Intermediates Revenue by Application (2018-2023)
5.2.2 Global Small Molecule API and Intermediates Revenue by Application (2024-2029)
5.2.3 Global Small Molecule API and Intermediates Revenue Market Share by Application (2018-2029)
5.3 Global Small Molecule API and Intermediates Price by Application (2018-2029)
6 Key Companies Profiled
6.1 Asymchem
6.1.1 Asymchem Corporation Information
6.1.2 Asymchem Description and Business Overview
6.1.3 Asymchem Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.1.4 Asymchem Small Molecule API and Intermediates Product Portfolio
6.1.5 Asymchem Recent Developments/Updates
6.2 Cipla
6.2.1 Cipla Corporation Information
6.2.2 Cipla Description and Business Overview
6.2.3 Cipla Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.2.4 Cipla Small Molecule API and Intermediates Product Portfolio
6.2.5 Cipla Recent Developments/Updates
6.3 Merck
6.3.1 Merck Corporation Information
6.3.2 Merck Description and Business Overview
6.3.3 Merck Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.3.4 Merck Small Molecule API and Intermediates Product Portfolio
6.3.5 Merck Recent Developments/Updates
6.4 Aurobindo Pharma
6.4.1 Aurobindo Pharma Corporation Information
6.4.2 Aurobindo Pharma Description and Business Overview
6.4.3 Aurobindo Pharma Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.4.4 Aurobindo Pharma Small Molecule API and Intermediates Product Portfolio
6.4.5 Aurobindo Pharma Recent Developments/Updates
6.5 Teva Pharmaceutical Industries
6.5.1 Teva Pharmaceutical Industries Corporation Information
6.5.2 Teva Pharmaceutical Industries Description and Business Overview
6.5.3 Teva Pharmaceutical Industries Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.5.4 Teva Pharmaceutical Industries Small Molecule API and Intermediates Product Portfolio
6.5.5 Teva Pharmaceutical Industries Recent Developments/Updates
6.6 Viatris
6.6.1 Viatris Corporation Information
6.6.2 Viatris Description and Business Overview
6.6.3 Viatris Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.6.4 Viatris Small Molecule API and Intermediates Product Portfolio
6.6.5 Viatris Recent Developments/Updates
6.7 Bristol-Myers Squibb
6.6.1 Bristol-Myers Squibb Corporation Information
6.6.2 Bristol-Myers Squibb Description and Business Overview
6.6.3 Bristol-Myers Squibb Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.4.4 Bristol-Myers Squibb Small Molecule API and Intermediates Product Portfolio
6.7.5 Bristol-Myers Squibb Recent Developments/Updates
6.8 Boehringer Ingelheim International
6.8.1 Boehringer Ingelheim International Corporation Information
6.8.2 Boehringer Ingelheim International Description and Business Overview
6.8.3 Boehringer Ingelheim International Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.8.4 Boehringer Ingelheim International Small Molecule API and Intermediates Product Portfolio
6.8.5 Boehringer Ingelheim International Recent Developments/Updates
6.9 AbbVie
6.9.1 AbbVie Corporation Information
6.9.2 AbbVie Description and Business Overview
6.9.3 AbbVie Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.9.4 AbbVie Small Molecule API and Intermediates Product Portfolio
6.9.5 AbbVie Recent Developments/Updates
6.10 Sun Pharmaceutical Industries
6.10.1 Sun Pharmaceutical Industries Corporation Information
6.10.2 Sun Pharmaceutical Industries Description and Business Overview
6.10.3 Sun Pharmaceutical Industries Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.10.4 Sun Pharmaceutical Industries Small Molecule API and Intermediates Product Portfolio
6.10.5 Sun Pharmaceutical Industries Recent Developments/Updates
6.11 Dr. Reddy's Laboratories
6.11.1 Dr. Reddy's Laboratories Corporation Information
6.11.2 Dr. Reddy's Laboratories Small Molecule API and Intermediates Description and Business Overview
6.11.3 Dr. Reddy's Laboratories Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.11.4 Dr. Reddy's Laboratories Small Molecule API and Intermediates Product Portfolio
6.11.5 Dr. Reddy's Laboratories Recent Developments/Updates
6.12 Albermarle Corporation
6.12.1 Albermarle Corporation Corporation Information
6.12.2 Albermarle Corporation Small Molecule API and Intermediates Description and Business Overview
6.12.3 Albermarle Corporation Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.12.4 Albermarle Corporation Small Molecule API and Intermediates Product Portfolio
6.12.5 Albermarle Corporation Recent Developments/Updates
6.13 Cytovance Biologics
6.13.1 Cytovance Biologics Corporation Information
6.13.2 Cytovance Biologics Small Molecule API and Intermediates Description and Business Overview
6.13.3 Cytovance Biologics Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.13.4 Cytovance Biologics Small Molecule API and Intermediates Product Portfolio
6.13.5 Cytovance Biologics Recent Developments/Updates
6.14 Zhejiang Ausun Pharmaceutical
6.14.1 Zhejiang Ausun Pharmaceutical Corporation Information
6.14.2 Zhejiang Ausun Pharmaceutical Small Molecule API and Intermediates Description and Business Overview
6.14.3 Zhejiang Ausun Pharmaceutical Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.14.4 Zhejiang Ausun Pharmaceutical Small Molecule API and Intermediates Product Portfolio
6.14.5 Zhejiang Ausun Pharmaceutical Recent Developments/Updates
6.15 Zhejiang Jiuzhou Pharmaceutical
6.15.1 Zhejiang Jiuzhou Pharmaceutical Corporation Information
6.15.2 Zhejiang Jiuzhou Pharmaceutical Small Molecule API and Intermediates Description and Business Overview
6.15.3 Zhejiang Jiuzhou Pharmaceutical Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.15.4 Zhejiang Jiuzhou Pharmaceutical Small Molecule API and Intermediates Product Portfolio
6.15.5 Zhejiang Jiuzhou Pharmaceutical Recent Developments/Updates
6.16 Shenzhen BORUI Pharmaceutical Technology
6.16.1 Shenzhen BORUI Pharmaceutical Technology Corporation Information
6.16.2 Shenzhen BORUI Pharmaceutical Technology Small Molecule API and Intermediates Description and Business Overview
6.16.3 Shenzhen BORUI Pharmaceutical Technology Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.16.4 Shenzhen BORUI Pharmaceutical Technology Small Molecule API and Intermediates Product Portfolio
6.16.5 Shenzhen BORUI Pharmaceutical Technology Recent Developments/Updates
6.17 Shanghai Haoyuan Chemexpress
6.17.1 Shanghai Haoyuan Chemexpress Corporation Information
6.17.2 Shanghai Haoyuan Chemexpress Small Molecule API and Intermediates Description and Business Overview
6.17.3 Shanghai Haoyuan Chemexpress Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.17.4 Shanghai Haoyuan Chemexpress Small Molecule API and Intermediates Product Portfolio
6.17.5 Shanghai Haoyuan Chemexpress Recent Developments/Updates
6.18 Hangzhou Xinqiao Biotechnology
6.18.1 Hangzhou Xinqiao Biotechnology Corporation Information
6.18.2 Hangzhou Xinqiao Biotechnology Small Molecule API and Intermediates Description and Business Overview
6.18.3 Hangzhou Xinqiao Biotechnology Small Molecule API and Intermediates Sales, Revenue and Gross Margin (2018-2023)
6.18.4 Hangzhou Xinqiao Biotechnology Small Molecule API and Intermediates Product Portfolio
6.18.5 Hangzhou Xinqiao Biotechnology Recent Developments/Updates
7 Industry Chain and Sales Channels Analysis
7.1 Small Molecule API and Intermediates Industry Chain Analysis
7.2 Small Molecule API and Intermediates Key Raw Materials
7.2.1 Key Raw Materials
7.2.2 Raw Materials Key Suppliers
7.3 Small Molecule API and Intermediates Production Mode & Process
7.4 Small Molecule API and Intermediates Sales and Marketing
7.4.1 Small Molecule API and Intermediates Sales Channels
7.4.2 Small Molecule API and Intermediates Distributors
7.5 Small Molecule API and Intermediates Customers
8 Small Molecule API and Intermediates Market Dynamics
8.1 Small Molecule API and Intermediates Industry Trends
8.2 Small Molecule API and Intermediates Market Drivers
8.3 Small Molecule API and Intermediates Market Challenges
8.4 Small Molecule API and Intermediates Market Restraints
9 Research Finding and Conclusion
10 Methodology and Data Source
10.1 Methodology/Research Approach
10.1.1 Research Programs/Design
10.1.2 Market Size Estimation
10.1.3 Market Breakdown and Data Triangulation
10.2 Data Source
10.2.1 Secondary Sources
10.2.2 Primary Sources
10.3 Author List
10.4 Disclaimer
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