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HEPES-Global Market Insights and Sales Trends 2025
Synopsis
HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid) is a zwitterionic sulfonic acid buffering agent; one of the twenty Good's buffers. HEPES is widely used in cell culture, largely because it is better at maintaining physiological pH despite changes in carbon dioxide concentration (produced by aerobic respiration) when compared to bicarbonate buffers, which are also commonly used in cell culture.
The global HEPES market size is expected to reach US$ 111.3 million by 2029, growing at a CAGR of 8.8% from 2023 to 2029. The market is mainly driven by the significant applications of HEPES in various end use industries. The expanding demands from the Cell Culture, IVD Reagents and Others,, are propelling HEPES market. HEPES Powder, one of the segments analysed in this report, is projected to record % CAGR and reach US$ million by the end of the analysis period. Growth in the HEPES Solution segment is estimated at % CAGR for the next seven-year period.
Global 5 largest manufacturers of HEPES are Merck, Suzhou Yacoo, Hopax, Avantor and ITW Reagents, which make up nearly 40%. Among them, Merck dominates with nearly 10% production value share, followed by Suzhou Yacoo (9%) and Hopax (8%). Top manufacturers are based in North America, China and Europe.
North America is the largest market, holding a share over 40%, followed by China and Europe, with shares 20% and 22% separately.
Based on the product type, the HEPES is primarily split into HEPES Powder and HEPES Solution. The leading type is HEPES Powder, with a market share over 75%.
Based on the Application, the HEPES is primarily split into Cell Culture and IVD Reagents. The largest segment is Cell Culture, accounting for over 50%.
Report Objectives
This report provides market insight on the different segments, by manufacturers, by Type, by Application. Market size and forecast (2018-2029) has been provided in the report. The primary objectives of this report are to provide 1) global market size and forecasts, growth rates, market dynamics, industry structure and developments, market situation, trends; 2) global market share and ranking by company; 3) comprehensive presentation of the global market for HEPES, with both quantitative and qualitative analysis through detailed segmentation; 4) detailed value chain analysis and review of growth factors essential for the existing market players and new entrants; 5) emerging opportunities in the market and the future impact of major drivers and restraints of the market.
Key Features of The Study:
This report provides in-depth analysis of the global HEPES market, and provides market size (US$ million) and CAGR for the forecast period (2023-2029), considering 2022 as the base year.
This report profiles key players in the global HEPES market based on the following parameters - company details (found date, headquarters, manufacturing bases), products portfolio, HEPES sales data, market share and ranking.
This report elucidates potential market opportunities across different segments and explains attractive investment proposition matrices for this market.
This report illustrates key insights about market drivers, restraints, opportunities, market trends, regional outlook.
Key companies of HEPES covered in this report include Merck, Thermo Fisher, Avantor, Lonza, Cytiva, Promega, ITW Reagents, Spectrum Chemical and Biological Industries, etc.
The global HEPES market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts.
Market Segmentation
Company Profiles:
Merck
Thermo Fisher
Avantor
Lonza
Cytiva
Promega
ITW Reagents
Spectrum Chemical
Biological Industries
Bio-Techne
BioSpectra
Corning
FUJIFILM Irvine Scientific
Dojindo Laboratories
Hopax
Suzhou Yacoo
XZL Bio-Technology
Yunbang Bio-pharmaceutical
Nanjing Robiot
Huanggang Yongan
Global HEPES market, by region:
North America (U.S., Canada, Mexico)
Europe (Germany, France, UK, Italy, etc.)
Asia Pacific (China, Japan, South Korea, Southeast Asia, India, etc.)
South America (Brazil, etc.)
Middle East and Africa (Turkey, GCC Countries, Africa, etc.)
Global HEPES market, Segment by Type:
HEPES Powder
HEPES Solution
Global HEPES market, by Application
Cell Culture
IVD Reagents
Others
Core Chapters
Chapter One: Introduces the study scope of this report, executive summary of market segments by Type, market size segments for North America, Europe, Asia Pacific, South America, Middle East & Africa.
Chapter Two: Detailed analysis of HEPES manufacturers competitive landscape, price, sales, revenue, market share and ranking, latest development plan, merger, and acquisition information, etc.
Chapter Three: Sales, revenue of HEPES in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the future development prospects, and market space in the world.
Chapter Four: Introduces market segments by Application, market size segment for North America, Europe, Asia Pacific, South America, Middle East & Africa.
Chapter Five, Six, Seven, Eight and Nine: North America, Europe, Asia Pacific, South America, Middle East & Africa, sales and revenue by country.
Chapter Ten: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter Eleven: Analysis of industrial chain, key raw materials, manufacturing cost, and market dynamics. Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter Twelve: Analysis of sales channel, distributors and customers.
Chapter Thirteen: Research Findings and Conclusion.
HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid) is a zwitterionic sulfonic acid buffering agent; one of the twenty Good's buffers. HEPES is widely used in cell culture, largely because it is better at maintaining physiological pH despite changes in carbon dioxide concentration (produced by aerobic respiration) when compared to bicarbonate buffers, which are also commonly used in cell culture.
The global HEPES market size is expected to reach US$ 111.3 million by 2029, growing at a CAGR of 8.8% from 2023 to 2029. The market is mainly driven by the significant applications of HEPES in various end use industries. The expanding demands from the Cell Culture, IVD Reagents and Others,, are propelling HEPES market. HEPES Powder, one of the segments analysed in this report, is projected to record % CAGR and reach US$ million by the end of the analysis period. Growth in the HEPES Solution segment is estimated at % CAGR for the next seven-year period.
Global 5 largest manufacturers of HEPES are Merck, Suzhou Yacoo, Hopax, Avantor and ITW Reagents, which make up nearly 40%. Among them, Merck dominates with nearly 10% production value share, followed by Suzhou Yacoo (9%) and Hopax (8%). Top manufacturers are based in North America, China and Europe.
North America is the largest market, holding a share over 40%, followed by China and Europe, with shares 20% and 22% separately.
Based on the product type, the HEPES is primarily split into HEPES Powder and HEPES Solution. The leading type is HEPES Powder, with a market share over 75%.
Based on the Application, the HEPES is primarily split into Cell Culture and IVD Reagents. The largest segment is Cell Culture, accounting for over 50%.
Report Objectives
This report provides market insight on the different segments, by manufacturers, by Type, by Application. Market size and forecast (2018-2029) has been provided in the report. The primary objectives of this report are to provide 1) global market size and forecasts, growth rates, market dynamics, industry structure and developments, market situation, trends; 2) global market share and ranking by company; 3) comprehensive presentation of the global market for HEPES, with both quantitative and qualitative analysis through detailed segmentation; 4) detailed value chain analysis and review of growth factors essential for the existing market players and new entrants; 5) emerging opportunities in the market and the future impact of major drivers and restraints of the market.
Key Features of The Study:
This report provides in-depth analysis of the global HEPES market, and provides market size (US$ million) and CAGR for the forecast period (2023-2029), considering 2022 as the base year.
This report profiles key players in the global HEPES market based on the following parameters - company details (found date, headquarters, manufacturing bases), products portfolio, HEPES sales data, market share and ranking.
This report elucidates potential market opportunities across different segments and explains attractive investment proposition matrices for this market.
This report illustrates key insights about market drivers, restraints, opportunities, market trends, regional outlook.
Key companies of HEPES covered in this report include Merck, Thermo Fisher, Avantor, Lonza, Cytiva, Promega, ITW Reagents, Spectrum Chemical and Biological Industries, etc.
The global HEPES market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts.
Market Segmentation
Company Profiles:
Merck
Thermo Fisher
Avantor
Lonza
Cytiva
Promega
ITW Reagents
Spectrum Chemical
Biological Industries
Bio-Techne
BioSpectra
Corning
FUJIFILM Irvine Scientific
Dojindo Laboratories
Hopax
Suzhou Yacoo
XZL Bio-Technology
Yunbang Bio-pharmaceutical
Nanjing Robiot
Huanggang Yongan
Global HEPES market, by region:
North America (U.S., Canada, Mexico)
Europe (Germany, France, UK, Italy, etc.)
Asia Pacific (China, Japan, South Korea, Southeast Asia, India, etc.)
South America (Brazil, etc.)
Middle East and Africa (Turkey, GCC Countries, Africa, etc.)
Global HEPES market, Segment by Type:
HEPES Powder
HEPES Solution
Global HEPES market, by Application
Cell Culture
IVD Reagents
Others
Core Chapters
Chapter One: Introduces the study scope of this report, executive summary of market segments by Type, market size segments for North America, Europe, Asia Pacific, South America, Middle East & Africa.
Chapter Two: Detailed analysis of HEPES manufacturers competitive landscape, price, sales, revenue, market share and ranking, latest development plan, merger, and acquisition information, etc.
Chapter Three: Sales, revenue of HEPES in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the future development prospects, and market space in the world.
Chapter Four: Introduces market segments by Application, market size segment for North America, Europe, Asia Pacific, South America, Middle East & Africa.
Chapter Five, Six, Seven, Eight and Nine: North America, Europe, Asia Pacific, South America, Middle East & Africa, sales and revenue by country.
Chapter Ten: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter Eleven: Analysis of industrial chain, key raw materials, manufacturing cost, and market dynamics. Introduces the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter Twelve: Analysis of sales channel, distributors and customers.
Chapter Thirteen: Research Findings and Conclusion.
Index1 HEPES Market Overview
1.1 HEPES Product Overview
1.2 HEPES Market Segment by Type
1.2.1 HEPES Powder
1.2.2 HEPES Solution
1.3 Global HEPES Market Size by Type
1.3.1 Global HEPES Market Size Overview by Type (2018-2029)
1.3.2 Global HEPES Historic Market Size Review by Type (2018-2023)
1.3.3 Global HEPES Forecasted Market Size by Type (2024-2029)
1.4 Key Regions Market Size Segment by Type
1.4.1 North America HEPES Sales Breakdown by Type (2018-2023)
1.4.2 Europe HEPES Sales Breakdown by Type (2018-2023)
1.4.3 Asia-Pacific HEPES Sales Breakdown by Type (2018-2023)
1.4.4 Latin America HEPES Sales Breakdown by Type (2018-2023)
1.4.5 Middle East and Africa HEPES Sales Breakdown by Type (2018-2023)
2 Global HEPES Market Competition by Company
2.1 Global Top Players by HEPES Sales (2018-2023)
2.2 Global Top Players by HEPES Revenue (2018-2023)
2.3 Global Top Players by HEPES Price (2018-2023)
2.4 Global Top Manufacturers HEPES Manufacturing Base Distribution, Sales Area, Product Type
2.5 HEPES Market Competitive Situation and Trends
2.5.1 HEPES Market Concentration Rate (2018-2023)
2.5.2 Global 5 and 10 Largest Manufacturers by HEPES Sales and Revenue in 2022
2.6 Global Top Manufacturers by Company Type (Tier 1, Tier 2 and Tier 3) & (based on the Revenue in HEPES as of 2022)
2.7 Date of Key Manufacturers Enter into HEPES Market
2.8 Key Manufacturers HEPES Product Offered
2.9 Mergers & Acquisitions, Expansion
3 HEPES Status and Outlook by Region
3.1 Global HEPES Market Size and CAGR by Region: 2018 VS 2022 VS 2029
3.2 Global HEPES Historic Market Size by Region
3.2.1 Global HEPES Sales in Volume by Region (2018-2023)
3.2.2 Global HEPES Sales in Value by Region (2018-2023)
3.2.3 Global HEPES Sales (Volume & Value) Price and Gross Margin (2018-2023)
3.3 Global HEPES Forecasted Market Size by Region
3.3.1 Global HEPES Sales in Volume by Region (2024-2029)
3.3.2 Global HEPES Sales in Value by Region (2024-2029)
3.3.3 Global HEPES Sales (Volume & Value), Price and Gross Margin (2024-2029)
4 Global HEPES by Application
4.1 HEPES Market Segment by Application
4.1.1 Cell Culture
4.1.2 IVD Reagents
4.1.3 Others
4.2 Global HEPES Market Size by Application
4.2.1 Global HEPES Market Size Overview by Application (2018-2029)
4.2.2 Global HEPES Historic Market Size Review by Application (2018-2023)
4.2.3 Global HEPES Forecasted Market Size by Application (2024-2029)
4.3 Key Regions Market Size Segment by Application
4.3.1 North America HEPES Sales Breakdown by Application (2018-2023)
4.3.2 Europe HEPES Sales Breakdown by Application (2018-2023)
4.3.3 Asia-Pacific HEPES Sales Breakdown by Application (2018-2023)
4.3.4 Latin America HEPES Sales Breakdown by Application (2018-2023)
4.3.5 Middle East and Africa HEPES Sales Breakdown by Application (2018-2023)
5 North America HEPES by Country
5.1 North America HEPES Historic Market Size by Country
5.1.1 North America HEPES Market Size Growth Rate (CAGR) by Country: 2018 VS 2022 VS 2029
5.1.2 North America HEPES Sales in Volume by Country (2018-2023)
5.1.3 North America HEPES Sales in Value by Country (2018-2023)
5.2 North America HEPES Forecasted Market Size by Country
5.2.1 North America HEPES Sales in Volume by Country (2024-2029)
5.2.2 North America HEPES Sales in Value by Country (2024-2029)
6 Europe HEPES by Country
6.1 Europe HEPES Historic Market Size by Country
6.1.1 Europe HEPES Market Size Growth Rate (CAGR) by Country: 2018 VS 2022 VS 2029
6.1.2 Europe HEPES Sales in Volume by Country (2018-2023)
6.1.3 Europe HEPES Sales in Value by Country (2018-2023)
6.2 Europe HEPES Forecasted Market Size by Country
6.2.1 Europe HEPES Sales in Volume by Country (2024-2029)
6.2.2 Europe HEPES Sales in Value by Country (2024-2029)
7 Asia-Pacific HEPES by Region
7.1 Asia-Pacific HEPES Historic Market Size by Region
7.1.1 Asia-Pacific HEPES Market Size Growth Rate (CAGR) by Region: 2018 VS 2022 VS 2029
7.1.2 Asia-Pacific HEPES Sales in Volume by Region (2018-2023)
7.1.3 Asia-Pacific HEPES Sales in Value by Region (2018-2023)
7.2 Asia-Pacific HEPES Forecasted Market Size by Region
7.2.1 Asia-Pacific HEPES Sales in Volume by Region (2024-2029)
7.2.2 Asia-Pacific HEPES Sales in Value by Region (2024-2029)
8 Latin America HEPES by Country
8.1 Latin America HEPES Historic Market Size by Country
8.1.1 Latin America HEPES Market Size Growth Rate (CAGR) by Country: 2018 VS 2022 VS 2029
8.1.2 Latin America HEPES Sales in Volume by Country (2018-2023)
8.1.3 Latin America HEPES Sales in Value by Country (2018-2023)
8.2 Latin America HEPES Forecasted Market Size by Country
8.2.1 Latin America HEPES Sales in Volume by Country (2024-2029)
8.2.2 Latin America HEPES Sales in Value by Country (2024-2029)
9 Middle East and Africa HEPES by Country
9.1 Middle East and Africa HEPES Historic Market Size by Country
9.1.1 Middle East and Africa HEPES Market Size Growth Rate (CAGR) by Country: 2018 VS 2022 VS 2029
9.1.2 Middle East and Africa HEPES Sales in Volume by Country (2018-2023)
9.1.3 Middle East and Africa HEPES Sales in Value by Country (2018-2023)
9.2 Middle East and Africa HEPES Forecasted Market Size by Country
9.2.1 Middle East and Africa HEPES Sales in Volume by Country (2024-2029)
9.2.2 Middle East and Africa HEPES Sales in Value by Country (2024-2029)
10 Company Profiles
10.1 Merck
10.1.1 Merck Company Information
10.1.2 Merck Introduction and Business Overview
10.1.3 Merck HEPES Sales, Revenue and Gross Margin (2018-2023)
10.1.4 Merck HEPES Products Offered
10.1.5 Merck Recent Development
10.2 Thermo Fisher
10.2.1 Thermo Fisher Company Information
10.2.2 Thermo Fisher Introduction and Business Overview
10.2.3 Thermo Fisher HEPES Sales, Revenue and Gross Margin (2018-2023)
10.2.4 Thermo Fisher HEPES Products Offered
10.2.5 Thermo Fisher Recent Development
10.3 Avantor
10.3.1 Avantor Company Information
10.3.2 Avantor Introduction and Business Overview
10.3.3 Avantor HEPES Sales, Revenue and Gross Margin (2018-2023)
10.3.4 Avantor HEPES Products Offered
10.3.5 Avantor Recent Development
10.4 Lonza
10.4.1 Lonza Company Information
10.4.2 Lonza Introduction and Business Overview
10.4.3 Lonza HEPES Sales, Revenue and Gross Margin (2018-2023)
10.4.4 Lonza HEPES Products Offered
10.4.5 Lonza Recent Development
10.5 Cytiva
10.5.1 Cytiva Company Information
10.5.2 Cytiva Introduction and Business Overview
10.5.3 Cytiva HEPES Sales, Revenue and Gross Margin (2018-2023)
10.5.4 Cytiva HEPES Products Offered
10.5.5 Cytiva Recent Development
10.6 Promega
10.6.1 Promega Company Information
10.6.2 Promega Introduction and Business Overview
10.6.3 Promega HEPES Sales, Revenue and Gross Margin (2018-2023)
10.6.4 Promega HEPES Products Offered
10.6.5 Promega Recent Development
10.7 ITW Reagents
10.7.1 ITW Reagents Company Information
10.7.2 ITW Reagents Introduction and Business Overview
10.7.3 ITW Reagents HEPES Sales, Revenue and Gross Margin (2018-2023)
10.7.4 ITW Reagents HEPES Products Offered
10.7.5 ITW Reagents Recent Development
10.8 Spectrum Chemical
10.8.1 Spectrum Chemical Company Information
10.8.2 Spectrum Chemical Introduction and Business Overview
10.8.3 Spectrum Chemical HEPES Sales, Revenue and Gross Margin (2018-2023)
10.8.4 Spectrum Chemical HEPES Products Offered
10.8.5 Spectrum Chemical Recent Development
10.9 Biological Industries
10.9.1 Biological Industries Company Information
10.9.2 Biological Industries Introduction and Business Overview
10.9.3 Biological Industries HEPES Sales, Revenue and Gross Margin (2018-2023)
10.9.4 Biological Industries HEPES Products Offered
10.9.5 Biological Industries Recent Development
10.10 Bio-Techne
10.10.1 Bio-Techne Company Information
10.10.2 Bio-Techne Introduction and Business Overview
10.10.3 Bio-Techne HEPES Sales, Revenue and Gross Margin (2018-2023)
10.10.4 Bio-Techne HEPES Products Offered
10.10.5 Bio-Techne Recent Development
10.11 BioSpectra
10.11.1 BioSpectra Company Information
10.11.2 BioSpectra Introduction and Business Overview
10.11.3 BioSpectra HEPES Sales, Revenue and Gross Margin (2018-2023)
10.11.4 BioSpectra HEPES Products Offered
10.11.5 BioSpectra Recent Development
10.12 Corning
10.12.1 Corning Company Information
10.12.2 Corning Introduction and Business Overview
10.12.3 Corning HEPES Sales, Revenue and Gross Margin (2018-2023)
10.12.4 Corning HEPES Products Offered
10.12.5 Corning Recent Development
10.13 FUJIFILM Irvine Scientific
10.13.1 FUJIFILM Irvine Scientific Company Information
10.13.2 FUJIFILM Irvine Scientific Introduction and Business Overview
10.13.3 FUJIFILM Irvine Scientific HEPES Sales, Revenue and Gross Margin (2018-2023)
10.13.4 FUJIFILM Irvine Scientific HEPES Products Offered
10.13.5 FUJIFILM Irvine Scientific Recent Development
10.14 Dojindo Laboratories
10.14.1 Dojindo Laboratories Company Information
10.14.2 Dojindo Laboratories Introduction and Business Overview
10.14.3 Dojindo Laboratories HEPES Sales, Revenue and Gross Margin (2018-2023)
10.14.4 Dojindo Laboratories HEPES Products Offered
10.14.5 Dojindo Laboratories Recent Development
10.15 Hopax
10.15.1 Hopax Company Information
10.15.2 Hopax Introduction and Business Overview
10.15.3 Hopax HEPES Sales, Revenue and Gross Margin (2018-2023)
10.15.4 Hopax HEPES Products Offered
10.15.5 Hopax Recent Development
10.16 Suzhou Yacoo
10.16.1 Suzhou Yacoo Company Information
10.16.2 Suzhou Yacoo Introduction and Business Overview
10.16.3 Suzhou Yacoo HEPES Sales, Revenue and Gross Margin (2018-2023)
10.16.4 Suzhou Yacoo HEPES Products Offered
10.16.5 Suzhou Yacoo Recent Development
10.17 XZL Bio-Technology
10.17.1 XZL Bio-Technology Company Information
10.17.2 XZL Bio-Technology Introduction and Business Overview
10.17.3 XZL Bio-Technology HEPES Sales, Revenue and Gross Margin (2018-2023)
10.17.4 XZL Bio-Technology HEPES Products Offered
10.17.5 XZL Bio-Technology Recent Development
10.18 Yunbang Bio-pharmaceutical
10.18.1 Yunbang Bio-pharmaceutical Company Information
10.18.2 Yunbang Bio-pharmaceutical Introduction and Business Overview
10.18.3 Yunbang Bio-pharmaceutical HEPES Sales, Revenue and Gross Margin (2018-2023)
10.18.4 Yunbang Bio-pharmaceutical HEPES Products Offered
10.18.5 Yunbang Bio-pharmaceutical Recent Development
10.19 Nanjing Robiot
10.19.1 Nanjing Robiot Company Information
10.19.2 Nanjing Robiot Introduction and Business Overview
10.19.3 Nanjing Robiot HEPES Sales, Revenue and Gross Margin (2018-2023)
10.19.4 Nanjing Robiot HEPES Products Offered
10.19.5 Nanjing Robiot Recent Development
10.20 Huanggang Yongan
10.20.1 Huanggang Yongan Company Information
10.20.2 Huanggang Yongan Introduction and Business Overview
10.20.3 Huanggang Yongan HEPES Sales, Revenue and Gross Margin (2018-2023)
10.20.4 Huanggang Yongan HEPES Products Offered
10.20.5 Huanggang Yongan Recent Development
11 Upstream, Opportunities, Challenges, Risks and Influences Factors Analysis
11.1 HEPES Key Raw Materials
11.1.1 Key Raw Materials
11.1.2 Key Raw Materials Price
11.1.3 Raw Materials Key Suppliers
11.2 Manufacturing Cost Structure
11.2.1 Raw Materials
11.2.2 Labor Cost
11.2.3 Manufacturing Expenses
11.3 HEPES Industrial Chain Analysis
11.4 HEPES Market Dynamics
11.4.1 HEPES Industry Trends
11.4.2 HEPES Market Drivers
11.4.3 HEPES Market Challenges
11.4.4 HEPES Market Restraints
12 Market Strategy Analysis, Distributors
12.1 Sales Channel
12.2 HEPES Distributors
12.3 HEPES Downstream Customers
13 Research Findings and Conclusion
14 Appendix
14.1 Research Methodology
14.1.1 Methodology/Research Approach
14.1.2 Data Source
14.2 Author Details
14.3 Disclaimer
Published By : QY Research
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