The Market Reports

Synopsis
The global market for L-Glutamine (Gln) was estimated to be worth US$ 221 million in 2024 and is forecast to a readjusted size of US$ 298 million by 2031 with a CAGR of 4.3% during the forecast period 2025-2031.
This report provides a comprehensive assessment of recent tariff adjustments and international strategic countermeasures on L-Glutamine (Gln) cross-border industrial footprints, capital allocation patterns, regional economic interdependencies, and supply chain reconfigurations.
L-Glutamine (commonly abbreviated as Gln) is a conditionally essential amino acid that plays a pivotal role in numerous physiological functions, including protein synthesis, immune response, and gut health. Structurally classified among the 20 standard amino acids, L-Glutamine contains an amide group derived from glutamic acid. It is the most abundant free amino acid in the human body, primarily synthesized in skeletal muscles and transported via the bloodstream to various tissues that require it for metabolic processes. L-Glutamine is deemed conditionally essential because, under normal circumstances, the body produces adequate amounts. However, during times of physical stress, such as trauma, surgery, infection, or intense exercise, the demand for L-Glutamine can exceed the body’s capacity to produce it, necessitating external supplementation.
In commercial form, L-Glutamine is typically produced via microbial fermentation, most commonly using genetically modified strains of bacteria such as Corynebacterium glutamicum or Escherichia coli. The industrial process involves fermenting carbohydrates such as glucose or molasses, followed by purification steps to isolate the amino acid. L-Glutamine is usually available in powdered form but can also be found in capsules, tablets, and functional food products such as protein shakes and fortified bars.
The primary applications of L-Glutamine are found in nutraceuticals, clinical nutrition, sports supplements, functional foods, and animal feed additives. In the healthcare and medical nutrition sector, L-Glutamine is utilized for its therapeutic benefits in treating conditions such as short bowel syndrome, Crohn’s disease, and to mitigate the side effects of chemotherapy. In sports and fitness, it is a popular supplement among athletes and bodybuilders to enhance muscle recovery, reduce fatigue, and prevent muscle catabolism. Its benefits in improving gut barrier integrity and immune system function also make it a valued ingredient in wellness and dietary supplement markets.
The global L-Glutamine market has witnessed steady growth over the past decade, driven by increasing health consciousness, a growing sports nutrition industry, and heightened demand for immune-boosting products in the wake of the COVID-19 pandemic. The North American and Asia-Pacific regions dominate the market, with Europe following closely behind. Key contributors to growth include rising demand in China and India for both human and animal nutrition applications, as well as technological advancements in amino acid fermentation.
Key Market Drivers
Rising Demand for Nutritional Supplements
The increasing prevalence of lifestyle-related disorders such as obesity, diabetes, and cardiovascular disease has spurred consumer interest in preventive healthcare and nutritional supplementation. L-Glutamine, with its multifunctional health benefits, fits well into the product portfolios of companies targeting these consumer needs. Additionally, growing awareness of the importance of gut health and immune support has further popularized glutamine supplementation.
Expanding Sports and Fitness Industry
The growth of the sports and fitness industry, driven by rising disposable income, increasing urbanization, and greater access to gyms and health clubs, has significantly influenced the L-Glutamine market. Athletes and fitness enthusiasts frequently incorporate glutamine supplements into their regimens to aid muscle recovery, reduce exercise-induced stress, and prevent muscle degradation, particularly in endurance sports or resistance training.
Therapeutic Applications in Clinical Nutrition
The use of L-Glutamine in medical nutrition therapy is another major growth driver. Hospitals and clinical settings use glutamine supplementation in enteral and parenteral nutrition for patients suffering from trauma, burns, or gastrointestinal disorders. Additionally, L-Glutamine has shown promising results in reducing mucositis in cancer patients undergoing chemotherapy or radiation therapy.
Shift Toward Preventive Healthcare
As healthcare systems worldwide move from treatment-centric to prevention-centric models, there has been a noticeable rise in demand for functional foods and dietary supplements. L-Glutamine fits into this trend due to its broad application across multiple wellness domains, including digestive health, metabolic health, and immune modulation.
Global L-Glutamine core manufacturers include Ajinomoto, Kyowa Hakko Kirin, Daesang, Meihua and Fufeng, etc. The top three manufacturers account for approximately 75% of the global share. The United States is the world's largest market, accounting for nearly 40% of the market.
This report aims to provide a comprehensive presentation of the global market for L-Glutamine (Gln), focusing on the total sales volume, sales revenue, price, key companies market share and ranking, together with an analysis of L-Glutamine (Gln) by region & country, by Type, and by Application.
The L-Glutamine (Gln) market size, estimations, and forecasts are provided in terms of sales volume (MT) and sales revenue ($ millions), considering 2024 as the base year, with history and forecast data for the period from 2020 to 2031. With both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding L-Glutamine (Gln).
Market Segmentation
By Company
Ajinomoto
Kyowa Hakko Kirin
Daesang
Meihua
Fufeng
Segment by Type
Pharmaceutical Grade
Nutraceutical Grade
Segment by Application
Dietary Supplements
Sports Nutrition
Clinical Nutrition
Food and Beverages
Pharmaceutical Use
By Region
North America
United States
Canada
Asia-Pacific
China
Japan
South Korea
Southeast Asia
India
Australia
Rest of Asia-Pacific
Europe
Germany
France
U.K.
Italy
Netherlands
Nordic Countries
Rest of Europe
Latin America
Mexico
Brazil
Rest of Latin America
Middle East & Africa
Turkey
Saudi Arabia
UAE
Rest of MEA
Chapter Outline
Chapter 1: Introduces the report scope of the report, global total market size (value, volume and price). This chapter also provides the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 2: Detailed analysis of L-Glutamine (Gln) manufacturers competitive landscape, price, sales and revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 3: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 4: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 5: Sales, revenue of L-Glutamine (Gln) in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the market development, future development prospects, market space, and market size of each country in the world.
Chapter 6: Sales, revenue of L-Glutamine (Gln) in country level. It provides sigmate data by Type, and by Application for each country/region.
Chapter 7: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 8: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 9: Conclusion.

Index