The Market Reports

Synopsis
The global market for PARP (Poly ADP-Ribose Polymerase) Inhibitor was estimated to be worth US$ 5551 million in 2024 and is forecast to a readjusted size of US$ 9999 million by 2031 with a CAGR of 8.9% during the forecast period 2025-2031.
PARP inhibitors are a group of pharmacological inhibitors of the enzyme poly ADP ribose polymerase (PARP). They are developed for multiple indications; the most important is the treatment of cancer. Several forms of cancer are more dependent on PARP than regular cells, making PARP an attractive target for cancer therapy. PARP inhibitors appear to improve progression-free survival in women with recurrent platinum-sensitive ovarian cancer, as evidenced mainly by olaparib added to conventional treatment. In our report, we only study four approved PARPi (Lynparza, Zejula, Rubraca and Talzenna). One unit is one tablet or one capsule.
Market Driver: The increasing prevalence of cancer, particularly ovarian, breast, and prostate cancers, is a major driver of the PARP inhibitors market. As targeted therapies become more popular for cancer treatment, PARP inhibitors, which work by blocking the repair of DNA damage in cancer cells, have shown promising results in clinical trials, especially for patients with specific genetic mutations such as BRCA1 and BRCA2. The growing recognition of the effectiveness of PARP inhibitors in both monotherapy and combination treatments is driving demand, as these therapies offer personalized treatment options with fewer side effects compared to traditional chemotherapy. Ongoing research and the expansion of indications for PARP inhibitors in other cancers also contribute to market growth.
Market Challenge: One of the key challenges for the PARP inhibitors market is the high cost of these therapies, which limits patient access and increases the financial burden on healthcare systems. Despite their effectiveness, the prices of PARP inhibitors are often prohibitively expensive, particularly for long-term use. Additionally, not all cancer patients benefit from PARP inhibition, and there is a risk of resistance developing over time, which can reduce the long-term efficacy of the drugs. Regulatory hurdles and the need for further clinical evidence to support broader indications also pose challenges to market expansion. As the market evolves, ensuring access and affordability while continuing to innovate will be critical to overcoming these barriers.
Global PARP (Poly ADP-Ribose Polymerase) Inhibitor key players include AstraZeneca, Tesaro, Merck & Co, etc. Global top three manufacturers hold a share about 90%. North America is the largest market, with a share about 70%, followed by Europe and Emerging Country, both have a share about 25 percent. In terms of product, Lynparza is the largest segment, with a share over 65%. And in terms of application, the largest application is Ovarian Cancer, followed by Breast Cancer.
This report aims to provide a comprehensive presentation of the global market for PARP (Poly ADP-Ribose Polymerase) Inhibitor, focusing on the total sales volume, sales revenue, price, key companies market share and ranking, together with an analysis of PARP (Poly ADP-Ribose Polymerase) Inhibitor by region & country, by Type, and by Application.
The PARP (Poly ADP-Ribose Polymerase) Inhibitor market size, estimations, and forecasts are provided in terms of sales volume (K Units) and sales revenue ($ millions), considering 2024 as the base year, with history and forecast data for the period from 2020 to 2031. With both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding PARP (Poly ADP-Ribose Polymerase) Inhibitor.
Market Segmentation
By Company
AstraZeneca
Tesaro
Merck & Co
Clovis Oncology
Pfizer
GSK
Zai Lab
Hengrui Medical
Segment by Type
Lynparza
Zejula
Rubraca
Talzenna
Other
Segment by Application
Ovarian Cancer
Breast Cancer
Other
By Region
North America
United States
Canada
Asia-Pacific
China
Japan
South Korea
Southeast Asia
India
Australia
Rest of Asia-Pacific
Europe
Germany
France
U.K.
Italy
Netherlands
Nordic Countries
Rest of Europe
Latin America
Mexico
Brazil
Rest of Latin America
Middle East & Africa
Turkey
Saudi Arabia
UAE
Rest of MEA
Chapter Outline
Chapter 1: Introduces the report scope of the report, global total market size (value, volume and price). This chapter also provides the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 2: Detailed analysis of PARP (Poly ADP-Ribose Polymerase) Inhibitor manufacturers competitive landscape, price, sales and revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 3: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 4: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 5: Sales, revenue of PARP (Poly ADP-Ribose Polymerase) Inhibitor in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the market development, future development prospects, market space, and market size of each country in the world.
Chapter 6: Sales, revenue of PARP (Poly ADP-Ribose Polymerase) Inhibitor in country level. It provides sigmate data by Type, and by Application for each country/region.
Chapter 7: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 8: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 9: Conclusion.

Index