The Market Reports

Synopsis
The global market for Tris(hydroxymethyl)aminomethane was estimated to be worth US$ 641 million in 2024 and is forecast to a readjusted size of US$ 2929 million by 2031 with a CAGR of 24.6% during the forecast period 2025-2031.
Tris, or Tris(hydroxymethyl)aminomethane, or known during medical use as tromethamine or THAM, is an organic compound with the formula (HOCH2)3CNH2. It is extensively used in biochemistry and molecular biology as a component of buffer solutions such as in TAE and TBE buffers, especially for solutions of nucleic acids. It contains a primary amine and thus undergoes the reactions associated with typical amines, e.g. condensations with aldehydes. Tris also complexes with metal ions in solution. In medicine, tromethamine is occasionally used as a drug, given in intensive care for its properties as a buffer for the treatment of severe metabolic acidosis in specific circumstances. Some medications are formulated as the "tromethamine salt" including hemabate (carboprost as trometamol salt), and "ketorolac trometamol"
The global key manufacturers of Tris(hydroxymethyl)Aminomethane are Suzhou Yacoo Science, ANGUS Chemical, and Jiangsu Tianjiayi Chemical, which togrther hold a share of nearly 98%. Chemical is the largest global producer with about 75% share, followed by Suzhou Yacoo Science with about 20% share. North America is the largest global production region with about 50% share, followed by Europe and China with 25% and 20% respectively. In terms of product type, standard grade is the largest segment with about 72% share, while in terms of application, bio-buffer is the largest downstream segment with about 75% share.
Market drivers and future development trends
Market drivers:
The rapid development of the pharmaceutical industry is one of the main factors driving the growth of market demand for tris(hydroxymethyl)aminomethane. In addition, the rapid development of biotechnology, chemical industry and other fields has also provided new growth points for the tris(hydroxymethyl)aminomethane market.
Future development trends:
With the continuous growth of demand for tris(hydroxymethyl)aminomethane in the field of pharmaceutical intermediates and the continuous development of biotechnology, chemical industry and other fields, the tris(hydroxymethyl)aminomethane market will usher in a broader development space. At the same time, with the continuous advancement of technology and the gradual reduction of costs, the application field of tris(hydroxymethyl)aminomethane will also be further expanded.
This report aims to provide a comprehensive presentation of the global market for Tris(hydroxymethyl)aminomethane, focusing on the total sales volume, sales revenue, price, key companies market share and ranking, together with an analysis of Tris(hydroxymethyl)aminomethane by region & country, by Type, and by Application.
The Tris(hydroxymethyl)aminomethane market size, estimations, and forecasts are provided in terms of sales volume (MT) and sales revenue ($ millions), considering 2024 as the base year, with history and forecast data for the period from 2020 to 2031. With both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Tris(hydroxymethyl)aminomethane.
Market Segmentation
By Company
Suzhou Yacoo Science
ANGUS Chemical
Jiangsu Tianjiayi Chemical
Segment by Type
Industrial Grade
Standard Grade
Ultra Pure Grade
Segment by Application
Biological Buffer
Pharmaceutical Intermediates
Others
By Region
North America
United States
Canada
Asia-Pacific
China
Japan
South Korea
Southeast Asia
India
Australia
Rest of Asia-Pacific
Europe
Germany
France
U.K.
Italy
Netherlands
Nordic Countries
Rest of Europe
Latin America
Mexico
Brazil
Rest of Latin America
Middle East & Africa
Turkey
Saudi Arabia
UAE
Rest of MEA
Chapter Outline
Chapter 1: Introduces the report scope of the report, global total market size (value, volume and price). This chapter also provides the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 2: Detailed analysis of Tris(hydroxymethyl)aminomethane manufacturers competitive landscape, price, sales and revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 3: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 4: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 5: Sales, revenue of Tris(hydroxymethyl)aminomethane in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the market development, future development prospects, market space, and market size of each country in the world.
Chapter 6: Sales, revenue of Tris(hydroxymethyl)aminomethane in country level. It provides sigmate data by Type, and by Application for each country/region.
Chapter 7: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 8: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 9: Conclusion.

Index