The Market Reports

Synopsis

The global market for Tris(hydroxymethyl)aminomethane was estimated to be worth US$ 641 million in 2024 and is forecast to a readjusted size of US$ 2929 million by 2031 with a CAGR of 24.6% during the forecast period 2025-2031.

Tris, or Tris(hydroxymethyl)aminomethane, or known during medical use as tromethamine or THAM, is an organic compound with the formula (HOCH2)3CNH2. It is extensively used in biochemistry and molecular biology as a component of buffer solutions such as in TAE and TBE buffers, especially for solutions of nucleic acids. It contains a primary amine and thus undergoes the reactions associated with typical amines, e.g. condensations with aldehydes. Tris also complexes with metal ions in solution. In medicine, tromethamine is occasionally used as a drug, given in intensive care for its properties as a buffer for the treatment of severe metabolic acidosis in specific circumstances. Some medications are formulated as the "tromethamine salt" including hemabate (carboprost as trometamol salt), and "ketorolac trometamol"

The global key manufacturers of Tris(hydroxymethyl)Aminomethane are Suzhou Yacoo Science, ANGUS Chemical, and Jiangsu Tianjiayi Chemical, which togrther hold a share of nearly 98%. Chemical is the largest global producer with about 75% share, followed by Suzhou Yacoo Science with about 20% share. North America is the largest global production region with about 50% share, followed by Europe and China with 25% and 20% respectively. In terms of product type, standard grade is the largest segment with about 72% share, while in terms of application, bio-buffer is the largest downstream segment with about 75% share.

Market drivers and future development trends

Market drivers:
The rapid development of the pharmaceutical industry is one of the main factors driving the growth of market demand for tris(hydroxymethyl)aminomethane. In addition, the rapid development of biotechnology, chemical industry and other fields has also provided new growth points for the tris(hydroxymethyl)aminomethane market.

Future development trends:
With the continuous growth of demand for tris(hydroxymethyl)aminomethane in the field of pharmaceutical intermediates and the continuous development of biotechnology, chemical industry and other fields, the tris(hydroxymethyl)aminomethane market will usher in a broader development space. At the same time, with the continuous advancement of technology and the gradual reduction of costs, the application field of tris(hydroxymethyl)aminomethane will also be further expanded.

This report aims to provide a comprehensive presentation of the global market for Tris(hydroxymethyl)aminomethane, focusing on the total sales volume, sales revenue, price, key companies market share and ranking, together with an analysis of Tris(hydroxymethyl)aminomethane by region & country, by Type, and by Application.

The Tris(hydroxymethyl)aminomethane market size, estimations, and forecasts are provided in terms of sales volume (MT) and sales revenue ($ millions), considering 2024 as the base year, with history and forecast data for the period from 2020 to 2031. With both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Tris(hydroxymethyl)aminomethane.

Market Segmentation

By Company

• Suzhou Yacoo Science
• ANGUS Chemical
• Jiangsu Tianjiayi Chemical

Segment by Type

• Industrial Grade
• Standard Grade
• Ultra Pure Grade

Segment by Application

• Biological Buffer
• Pharmaceutical Intermediates
• Others

Segment by Region

• North America: United States, Canada, and Mexico
• Europe: United Kingdom, Germany, France, Spain, Italy, and Rest of Europe
• Asia Pacific: China, India, Japan, Australia, South Korea, and Rest of Asia Pacific
• Middle East & Africa: Saudi Arabia, South Africa, and Rest of MEA
• Latin America: Brazil, Argentina, and Rest of Latin America

*If you need a regional or country-specific version, or customized segmentation, we can tailor the report to your requirements.